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Table 3 Comparison of motivation to participate in the course between HPI and TUM

From: Implementation and evaluation of personal genetic testing as part of genomics analysis courses in German universities

Topic

HPI (n = 26)

TUM (n = 55)

P-value

Effect size (V)

General interest in genomics/genomic analyses

92% (24)

91% (50)

1

0 (small)

To receive/analyze my own genomic data

85% (22)

64% (35)

0.07

0.19 (small to medium)

Interest in pharmacogenomics (e.g., the impact of genomic variants on medication effects)

77% (20)

38% (21)

0.002

0.34 (medium to large)

To gain knowledge about genomics/genomic analyses to apply it in my professional career

69% (18)

62% (29)a

0.61

0.05 (small)

Interest in research topics like genome-wide association studies

58% (15)

45% (25)

0.35

0.09 (small)

To learn about tools for variant interpretation and analysis

54% (14)

64% (35)

0.47

0.07 (small)

Interest in ethical issues in the context of genomic analyses

50% (13)

53% (29)

1

0 (small)

Interest in legal foundations of genomic analyses

50% (13)

44% (24)

0.64

0.03 (small)

Interest in ancestry analysis

46% (12)

47% (26)

1

0 (small)

To receive the credit points

42% (11)

38% (3)b

1

0 (small)

Interest in commercial genomic testing (“direct-to-consumer testing”)

38% (10)

45% (25)

0.63

0.04 (small)

To better understand the situation of patients when undergoing genomic testing

38% (10)

45% (25)

0.63

0.04 (small)

  1. The p-values and effect sizes relate to the difference between answers provided by HPI and TUM participants. The information was assessed using HPI questionnaire Q4 2020 (n = 10), HPI questionnaire Q1 2021 (n = 16), TUM questionnaire Q4’ (n = 47), and TUM questionnaire Q1 2020/21 (n = 8). Q1 (pre-course) questionnaires were used where possible; questionnaire HPI Q4 2020 was used instead of Q1, as questions regarding the motivation to participate in the course differed considerably between the long- and short-version questionnaires. TUM Q4' was used, as this was the only questionnaire conducted for TUM courses taking place before the winter term 2020/21
  2. aThis question was included for TUM only in Q4’ (n = 47) and later included again for HPI questionnaires; it is missing in TUM Q1 2021/22
  3. bBefore the summer term 2021/22, students participating in GM did not receive credit points, therefore the question was only included for TUM Q1 2021/22 (n = 8) when the format was changed from a facultative to a compulsory elective course included in the curriculum