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Table 4 Details of the 45 cases with Bart’s hydrops

From: Genetic disorders and pregnancy outcomes of non-immune hydrops fetalis in a tertiary referral center

Case NO.

GA at diagnosis (weeks)

Maternal age

Ultrasound Imaging

Karyotype

 

outcomes

39

17

25

ascites, pericardial effusion, cardiomegaly

46, XX

 

TOP

40

17

33

ascites, pericardial effusion, cardiomegaly, placental thickening, MCA PSV >1.55MoM

46, XX

 

TOP

41

18

31

ascites, pericardial effusion, placental thickening, MCA PSV >1.55MoM

46, XX

 

TOP

42

19

29

ascites, pericardial effusion, placental thickening, cardiomegaly, MCA PSV >1.55MoM

46, XY

 

TOP

43

19

25

ascites, pericardial effusion, MCA PSV >1.55MoM

46, XX

 

TOP

44

19

28

ascites, pericardial effusion, placental thickening ,cardiomegaly ,MCA PSV >1.55MoM

46, XY

 

TOP

45

19

25

ascites, pleural effusion, placental thickening ,cardiomegaly ,MCA PSV >1.55MoM

46, XX

 

TOP

46

19

29

ascites, pericardial effusion, placental thickening ,cardiomegaly ,MCA PSV >1.55MoM

46, XX

 

TOP

47

20

18

ascites, pericardial effusion, placental thickening ,cardiomegaly ,MCA PSV >1.55MoM

46, XY

 

TOP

48

21

26

ascites, pericardial effusion

46, XX

 

TOP

49

21

32

ascites, pleural effusion

46, XX

 

TOP

50

21

29

generalized skin edema, MCA PSV >1.55MoM

46, XX

 

TOP

51

22

26

ascites, pericardial effusion, placental thickening, polyhydramnios

46, XX

 

TOP

52

22

30

ascites, pericardial effusion, placental thickening ,cardiomegaly ,MCA PSV >1.55MoM

46, XY

 

TOP

53

22

26

ascites, pericardial effusion ,cardiomegaly ,MCA PSV >1.55MoM

46, XX

 

TOP

54

23

26

ascites, pericardial effusion

46, XX

 

TOP

55

23

27

ascites, pericardial effusion, placental thickening, cardiomegaly

46, XY

 

TOP

56

23

31

generalized skin edema, ascites, pericardial effusion, placental thickening ,cardiomegaly ,MCA PSV >1.55MoM

46, XY

 

TOP

57

23

32

ascites, pericardial effusion, placental thickening ,cardiomegaly ,MCA PSV >1.55MoM

46, XY

 

TOP

58

23

38

pleural effusion, pericardial effusion, placental thickening ,cardiomegaly ,MCA PSV >1.55MoM

46, XX

 

TOP. Maternal mirror syndrome

59

24

26

ascites, pericardial effusion, cardiomegaly ,MCA PSV >1.55MoM

46, XX

 

TOP

60

24

28

ascites, pericardial effusion, cardiomegaly

46, XY

 

TOP

61

24

30

ascites, pericardial effusion, cardiomegaly, MCA PSV >1.55MoM

46, XY

 

TOP

62

24

28

ascites, pericardial effusion, FGR, cardiomegaly

46, XY

 

TOP

63

25

30

ascites, pericardial effusion, placental thickening, cardiomegaly

46, XX

 

TOP

64

25

28

ascites, pericardial effusion, FGR, cardiomegaly

46, XX

 

TOP

65

25

27

ascites, pericardial effusion, FGR, cardiomegaly

46, XY

 

TOP

66

25

24

ascites, pericardial effusion, cardiomegaly, MCA PSV >1.55MoM

46, XY

 

TOP

67

25

26

ascites, pericardial effusion, cardiomegaly

46, XY

 

TOP

68

26

28

ascites, pericardial effusion, placental thickening, cardiomegaly

46, XX

 

TOP

69

27

22

ascites, pericardial effusion, placental thickening, cardiomegaly

46, XY

 

TOP

70

27

23

ascites, pericardial effusion, cardiomegaly

46, XX

 

TOP

71

28

32

ascites, pericardial effusion, placental thickening, cardiomegaly

46, XY

 

TOP

72

29

28

ascites, pericardial effusion

46, XY

 

TOP

73

29

34

ascites, pericardial effusion, placental thickening, cardiomegaly

46, XX

 

TOP

74

29

31

ascites, pleural effusion, placental thickening, cardiomegaly, FGR

46, XX

 

TOP

75

30

30

ascites, pericardial effusion, cardiomegaly, polyhydramnios, FGR

46, XY

 

TOP

76

31

29

ascites, pericardial effusion, placental thickening, cardiomegaly

46, XX

 

Premature delivery,

END

77

31

35

ascites, pericardial effusion, placental thickening, cardiomegaly, local skin edema

46, XY

 

Premature delivery, END

78

31

30

ascites, pericardial effusion, placental thickening, cardiomegaly

46, XX

 

TOP

79

31

24

ascites, pericardial effusion, placental thickening, cardiomegaly, FGR

46, XX

 

IUFD

80

32

20

ascites, pericardial effusion, local skin edema, placental thickening, polyhydramnios, FGR

46, XY

 

Maternal mirror syndrome. Premature delivery, END

81

32

26

generalized skin edema, ascites, FGR

46, XY

 

TOP

82

32

18

ascites, bilateral pleural effusion, placental thickening ,cardiomegaly ,MCA PSV >1.55MoM

46, XX

 

Maternal mirror syndrome. Premature delivery, END

83

33

28

ascites, pericardial effusion, placental thickening, cardiomegaly

46, XY

 

TOP

  1. Abbreviations: TOP, termination of pregnancy; IUFD, intrauterine fetal demise; END, early neonatal death; FGR, fetal growth retardation; NT, nuchal translucency; MCV PSV, middle cerebral artery peak systolic velocity; MOM, multiples of the median