Traits | Consortium or Study | Number of SNPs | Sample size | Unit | Variance explained (%) | PMID |
---|---|---|---|---|---|---|
Cardiometabolic factors | ||||||
 BMI | GIANT | 60 | 322,154 | SD | 1.14 | 25,673,413 |
 WHR adjusted BMI | GIANT | 36 | 210,088 | SD | 0.94 | 25,673,412 |
 Height | GIANT | 357 | 253,288 | SD | 10.95 | 25,282,103 |
 Body fat percentage | – | 5 | 89,297 | SD | 0.23 | 26,833,246 |
 LDL cholesterol | GLGC | 286 | 842,635 | SD | 5.08 | 34,887,591 |
 Total triglycerides | GLGC | 337 | 864,202 | SD | 4.72 | 34,887,591 |
 Total cholesterol | GLGC | 338 | 930,666 | SD | 5.69 | 34,887,591 |
 HDL cholesterol | GLGC | 381 | 888,220 | SD | 6.18 | 34,887,591 |
 Fasting glucose | MAGIC | 64 | 200,622 | SD | 3.72 | 34,059,833 |
 Fasting insulin | MAGIC | 35 | 151,013 | SD | 1.19 | 34,059,833 |
Glycated hemoglobin (HbA1c) | MAGIC | 70 | 146,864 | SD | 5.40 | 34,059,833 |
 2 h glucose | MAGIC | 9 | 63,578 | SD | 1.11 | 34,059,833 |
 Type 2 diabetes mellitus | DIAGRAM | 86 | 455,313 | Log-odds | 1.27 | 30,297,969 |
 Systolic blood pressure | ICBP | 10 | 299,024 | 10 mmHg | 0.13 | 30,224,653 |
 Diastolic blood pressure | ICBP | 14 | 299,024 | 10 mmHg | 0.19 | 30,224,653 |
 Metabolic syndrome | UK Biobank | 60 | 291,107 | Log-odds | 1.97 | 31,589,552 |
Lifestyle and dietary factors | ||||||
 Smoking cessation | GSCAN | 4 | 143,851 | Log-odds | 0.12 | 30,643,251 |
 Smoking initiation (ever regular vs. never regular) | GSCAN | 10 | 249,171 | Log-odds | 0.15 | 30,643,251 |
 Smoking cigarettes per day | GSCAN | 9 | 143,210 | SD | 0.65 | 30,643,251 |
 Alcohol drinks per week | GSCAN | 5 | 226,223 | Drinks/week | 0.08 | 30,643,251 |
 Years of education | SSGAC | 47 | 293,723 | SD | 0.64 | 27,225,129 |
 Caffeine consumption from Tea, mg/day | UK Biobank | 22 | 395,866 | SD | 0.25 | 33,287,642 |
 Caffeine consumption from coffee or tea, mg/day | UK Biobank | 41 | 362,316 | SD | 0.84 | 33,287,642 |
 Glucocorticoids (medication use) | UK Biobank | 19 | 205,700 | SD | 0.63 | 31,015,401 |
 Accelerometer-based PA (acceleration average) | UK Biobank | 8 | 91,084 | SD | 0.30 | 29,899,525 |
 Moderate-to-vigorous PA | UK Biobank | 17 | 377,234 | SD | 0.15 | 29,899,525 |
 Vigorous PA | UK Biobank | 7 | 261,055 | SD | 0.11 | 29,899,525 |
 Income before tax | UK Biobank | 25 | 286,301 | SD | 0.35 | 31,844,048 |
 Intelligence | UK Biobank | 157 | 269,867 | SD | 2.50 | 29,942,086 |
 Leisure sedentary behavior (computer use) | UK Biobank | 45 | 408,815 | SD | 0.43 | 32,317,632 |
 Driving | UK Biobank | 4 | 408,815 | SD | 0.04 | 32,317,632 |
 Leisure sedentary behavior (television watching) | UK Biobank | 125 | 408,815 | SD | 1.31 | 32,317,632 |
 Meat-related diet | UK Biobank | 14 | 335,576 | SD | 0.14 | 32,066,663 |
 Fish and plant-related diet | UK Biobank | 22 | 335,576 | SD | 0.32 | 32,066,663 |
Biochemical measures | ||||||
 Serum vitamin B12 | Icelandic + Danish | 9 | 45,576 | SD | 5.00 | 23,754,956 |
 Serum Vitamin C | – | 7 | 52,018 | SD | 1.29 | 33,203,707 |
 Serum 25-hydroxyvitamin D | SUNLIGHT | 6 | 79,366 | SD | 2.23 | 29,343,764 |
 Serum magnesium | CHARGE | 5 | 23,829 | SD | 1.55 | 20,700,443 |
 Serum calcium | – | 5 | 61,011 | SD | 0.88 | 24,068,962 |
 Serum phosphorus | CHARGE | 5 | 21,734 | SD | 1.30 | 20,558,539 |
 Serum CRP | CHARGE | 17 | 204,402 | SD | 0.87 | 30,388,399 |
 Serum uric acid | GUGC | 15 | 110,347 | SD | 1.46 | 23,263,486 |
 Serum adiponectin | ADIPOGen | 13 | 29,347 | SD | 8.78 | 22,479,202 |
 Urine measures | ||||||
 Urine pH (pH <  = 5.0 vs pH > 5.0) | Iceland | 3 | 148,199 | Log-odds | 0.10 | 30,476,138 |
 Urinary sodium | UK Biobank | 48 | 446,237 | SD | 0.46 | 31,409,800 |
 Urinary potassium | UK Biobank | 20 | 446,230 | SD | 0.17 | 31,409,800 |