Fig. 2

Identification of differential expression and prognostic of ARGs in TCGA-BLCA. A GSEA showed that the apoptosis pathway are differentially enriched in BLCA patients. B Venn diagram to identify differentially expressed genes between tumor and normal tissue that were correlated with overall survival. C Volcano plot of differentially expressed ARGs between tumor and normal tissue. Dot stands for gene. Red dots represent up-regulated genes. D Forest plots showing the results of the univariate Cox regression between 8 ARGs and overall survival in BLCA. E Correlation heat map of 4 ARGs. F The illustration shows the expression distribution of 4 ARGs between stage 3&4 (red) and stage 1&2 (blue). G The illustration shows the expression distribution of 4 ARGs between PR&CR group (red) and PD&SD group (blue). H The illustration shows the expression distribution of 4 ARGs between radiation therapy group (red) and no radiation therapy group (blue). I The illustration shows the expression distribution of 4 ARGs between dead (red) and alive (blue). J The illustration shows the expression distribution of 4 ARGs between papillary group (red) and non-papillary group (blue). K The illustration shows the expression distribution of 4 ARGs between high grade group (red) and low grade (blue). L The illustration shows the expression distribution of 4 ARGs between smoker group (red) and no smoker group (blue). (*P < 0.05; **P < 0.01; ***P < 0.001)