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Table 2 Allelic distributions of the rs7779972 in patients with VKH and healthy controls

From: Association of ZC3HAV1 single nucleotide polymorphisms with the susceptibility of Vogt-Koyanagi-Harada Disease

Allele

VKH

Controls

P*

OR (95% CI) *

n (%)

n (%)

First

    

 A

262(35.2)

210(27.6)

0.001

1.429(1.148–1.778)

 G

482(64.8)

552(72.4)

0.001

0.700(0.562–0.871)

Second

    

 A

258(35.3)

312(30.4)

0.028

1.254(1.025–1.535)

 G

472(64.7)

716(69.6)

0.028

0.797(0.652–0.975)

Combined

  

P†

pooled OR (95% CI) †

 A

520(35.3)

522(29.2)

1.50 × 10 − 4

1.332(1.149–1.545)

 G

954(64.7)

1268(70.8)

1.50 × 10 − 4

0.751(0.647–0.871)

  1. VKH: Vogt-Koyanagi-Harada Disease; OR: odds ratio; 95% CI: 95% confidence interval.
  2. * χ2 test.
  3. † Cochran-Mantel-Haenszel test.
  4. P < 2.08 × 10− 3 (0.05/24) indicates statistical significance for each variant tested. Values with statistical significance are in boldface.
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BMC Medical Genomics

ISSN: 1755-8794

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