This section considers studies on the development, refinement and application of novel computational and statistical methods for the analysis of genetic and genomic data for the study of human health and disease, as well as the application of population genetic approaches.
Determining mutational burden and signature using RNA-seq from tumor-only samples
Traditionally, mutational burden and mutational signatures have been assessed by tumor-normal pair DNA sequencing. The requirement of having both normal and tumor samples is not always feasible from a clinical...
Citation: BMC Medical Genomics 2021 14:65