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Table 2 Genes downregulated in palmar fascia fibroblasts obtained from Dupuytren's Contracture using CodeLinkâ„¢ Platform.

From: Identification of differentially expressed genes in fibroblasts derived from patients with Dupuytren's Contracture

 

Gene ID

Gene Name

Fold Change

1.

NM_002847

Protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 1

0.16

2.

NM_021602

CD79B antigen (immunoglobulin-associated beta) (CD79B), transcript variant 2

0.18

3.

NM_001831

Clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) (CLU), transcript variant 1

0.21

4.

NM_004000

chitinase-3-like 2 (CHI3L2)

0.22

5.

NM_152536

FYVE, RhoGEF and PH domain containing 5 (FGD5), mRNA

0.25

6.

NM_000668

Alcohol dehydrogenase 1B (class I), beta polypeptide (ADH1B)

0.29

7.

NM_001831

clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) (CLU), transcript variant 1

0.30

8.

NM_005410

selenoprotein P, plasma, 1 (SEPP1)

0.34

9.

NM_005525

hydroxysteroid (11-beta)dehydrogenase 1 (HSD11B1), transcript variant 1

0.35

10.

NM_145244

DNA-damage inducible transcript 4-like (DDIT4L)

0.37

11.

NM_012168

F-box protein 2 (FBXO2), mRNA

0.38

12.

NM_021146

angiopoietin-like factor (CDT6)

0.39

13.

U83115

Non-lens beta gamma-crystallin like protein (AIM1)mRNA

0.42

14.

NM_001801

cysteine dioxygenase type1 (CDO1)

0.45

15.

NM_005627

serum/glucocorticoid regulated kinase (SGK)

0.49

16.

NM_002928

Regulator of G-protein signaling 16 (RGS16)

0.49

17.

NM_000690

aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2), nuclear gene encoding mitochondrial protein

0.54

18.

NM_005391

pyruvate dehydrogenase kinase, isoenzyme 3 (PDK3)

0.55

19.

NM_000636

superoxide dismutase 2, mitochondrial (SOD2)

0.56

20.

NM_006391

Importin 7 (IPO7)

0.57

21.

NM_030968

C1q and tumor necrosis factor related protein 1 (C1QTNF1), transcript variant 1

0.58

22.

NM_001353

aldo-keto reductase family 1, member C1 (dihyrdodiol dehydrogenase 1;20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1)

0.59

cDNA of Unknown Biological Function

1.

D52654

HUM084D02B Clontech human fetal brain polyA+ mRNA (#6535) cDNA clone GEN-084D02 5'

0.00

2.

AI597810

tu91f07x1 NCI_CGAP_Gas4 cDNA clone IMAGE:2258437 3' similar to contains L1.t1 L1 L1 repetitive element;

0.01

3.

H90897

yu89c07s1 Soares fetal liver spleen 1NFLS cDNA clone IMAGE:240972 3'

0.10

4.

NM_021602

CD79B antigen (immunoglobulin-associated beta) (CD79B), transcript variant 2

0.18

5.

BX094389

NCI_CGAP_Ut4 cDNA clone IMAGp998O234898

0.23

6.

NM_152536

FYVE, RhoGEF and PH domain containing 5 (FGD5), mRNA

0.25

7.

AK054990

cDNA FLJ30428 fis, clone BRACE2008941

0.31

8.

AA866107

oh53b03.s1 NCI_CGAP_GC4 cDNA clone IMAGE:1470317 3'

0.33

9.

BU624020

UI-H-FG1-bgh-h-24-0-UIs1 NCI_CGAP_FG1 cDNA clone UI-H-FG1-bgh-h-24-0-UI 3'

0.34

10.

AI186220

qd34a02x1 Soares_fetal_heart_NbHH19W cDNA clone IMAGE:1731338 3'

0.35

11.

BG117761

602350442F1 NIH_MGC_90 cDNA clone IMAGE:4445147 5'

0.40

12.

BM929454

UI-E-EJ1-aje-b-23-0-UIr1 UI-E-EJ1 cDNA clone UI-E-EJ1-aje-b-23-0-UI 5'

0.42

13.

AL117425

mRNA; cDNA DKFZp566L203 (from clone DKFZp566L203)

0.43

14.

BQ430788

AGENCOURT_7776027 NIH_MGC_68 cDNA clone IMAGE:6024295 5'

0.44

15.

AA594928

no40a05s1 NCI_CGAP_Pr23 cDNA clone IMAGE:1103120 3'

0.46

16.

H05195

yl85f06r1 Soares infant brain 1NIB cDNA clone IMAGE:45005 5'

0.47

17.

AK124841

cDNA FLJ42851 fis, clone BRHIP2005719

0.47

18.

H05195

yl85f06r1 Soares infant brain 1NIB cDNA clone IMAGE:45005 5'

0.48

19.

AL119769

DKFZp761E1224_r1 761 (synonym: hamy2) cDNA clone DKFZp761E1224 5'

0.54

20.

AI094001

qa28a03s1 Soares_NhHMPu_S1 cDNA clone IMAGE:1688044 3'

0.54

21.

AL133055

mRNA; cDNA DKFZp434J1015 (from clone DKFZp434J1015)

0.56

22.

BX094154

Soares fetal liver spleen 1NFLS cDNA clone IMAGp998P17654

0.58

23.

W67378

zd40b03r1 Soares_fetal_heart_NbHH19W cDNA clone IMAGE:343085 5' similar to SW:DHAM_HUMAN P05091 ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR;

0.58

24.

BM829211

K-EST0102153 S9SNU601 cDNA clone S9SNU601-57-C10 5'

0.58

25.

BM711907

UI-E-CL1-afc-i-20-0-UIr1 UI-E-CL1 cDNA clone UI-E-CL1-afc-i-20-0-UI 5'

0.59

26.

BX088944

Soares_testis_NHT cDNA clone MAGp998J113516; IMAGE:1392490

0.72

27.

BC033399

clone IMAGE:4829538

0.77

28.

CB960582

AGENCOURT_13892014 NIH_MGC_147 cDNA clone IMAGE:30343321 5'

0.79

29.

BC034566

clone IMAGE:4821877, mRNA

0.79

  1. SAM analysis was performed to identify the statistically significant differentially expressed genes. Genes that are common to both platforms are highlighted as Bold and Italics.