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Table 2 Genes downregulated in palmar fascia fibroblasts obtained from Dupuytren's Contracture using CodeLink™ Platform.

From: Identification of differentially expressed genes in fibroblasts derived from patients with Dupuytren's Contracture

  Gene ID Gene Name Fold Change
1. NM_002847 Protein tyrosine phosphatase, receptor type, N polypeptide 2 (PTPRN2), transcript variant 1 0.16
2. NM_021602 CD79B antigen (immunoglobulin-associated beta) (CD79B), transcript variant 2 0.18
3. NM_001831 Clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) (CLU), transcript variant 1 0.21
4. NM_004000 chitinase-3-like 2 (CHI3L2) 0.22
5. NM_152536 FYVE, RhoGEF and PH domain containing 5 (FGD5), mRNA 0.25
6. NM_000668 Alcohol dehydrogenase 1B (class I), beta polypeptide (ADH1B) 0.29
7. NM_001831 clusterin (complement lysis inhibitor, SP-40,40, sulfated glycoprotein 2, testosterone-repressed prostate message 2, apolipoprotein J) (CLU), transcript variant 1 0.30
8. NM_005410 selenoprotein P, plasma, 1 (SEPP1) 0.34
9. NM_005525 hydroxysteroid (11-beta)dehydrogenase 1 (HSD11B1), transcript variant 1 0.35
10. NM_145244 DNA-damage inducible transcript 4-like (DDIT4L) 0.37
11. NM_012168 F-box protein 2 (FBXO2), mRNA 0.38
12. NM_021146 angiopoietin-like factor (CDT6) 0.39
13. U83115 Non-lens beta gamma-crystallin like protein (AIM1)mRNA 0.42
14. NM_001801 cysteine dioxygenase type1 (CDO1) 0.45
15. NM_005627 serum/glucocorticoid regulated kinase (SGK) 0.49
16. NM_002928 Regulator of G-protein signaling 16 (RGS16) 0.49
17. NM_000690 aldehyde dehydrogenase 2 family (mitochondrial) (ALDH2), nuclear gene encoding mitochondrial protein 0.54
18. NM_005391 pyruvate dehydrogenase kinase, isoenzyme 3 (PDK3) 0.55
19. NM_000636 superoxide dismutase 2, mitochondrial (SOD2) 0.56
20. NM_006391 Importin 7 (IPO7) 0.57
21. NM_030968 C1q and tumor necrosis factor related protein 1 (C1QTNF1), transcript variant 1 0.58
22. NM_001353 aldo-keto reductase family 1, member C1 (dihyrdodiol dehydrogenase 1;20-alpha (3-alpha)-hydroxysteroid dehydrogenase) (AKR1C1) 0.59
cDNA of Unknown Biological Function
1. D52654 HUM084D02B Clontech human fetal brain polyA+ mRNA (#6535) cDNA clone GEN-084D02 5' 0.00
2. AI597810 tu91f07x1 NCI_CGAP_Gas4 cDNA clone IMAGE:2258437 3' similar to contains L1.t1 L1 L1 repetitive element; 0.01
3. H90897 yu89c07s1 Soares fetal liver spleen 1NFLS cDNA clone IMAGE:240972 3' 0.10
4. NM_021602 CD79B antigen (immunoglobulin-associated beta) (CD79B), transcript variant 2 0.18
5. BX094389 NCI_CGAP_Ut4 cDNA clone IMAGp998O234898 0.23
6. NM_152536 FYVE, RhoGEF and PH domain containing 5 (FGD5), mRNA 0.25
7. AK054990 cDNA FLJ30428 fis, clone BRACE2008941 0.31
8. AA866107 oh53b03.s1 NCI_CGAP_GC4 cDNA clone IMAGE:1470317 3' 0.33
9. BU624020 UI-H-FG1-bgh-h-24-0-UIs1 NCI_CGAP_FG1 cDNA clone UI-H-FG1-bgh-h-24-0-UI 3' 0.34
10. AI186220 qd34a02x1 Soares_fetal_heart_NbHH19W cDNA clone IMAGE:1731338 3' 0.35
11. BG117761 602350442F1 NIH_MGC_90 cDNA clone IMAGE:4445147 5' 0.40
12. BM929454 UI-E-EJ1-aje-b-23-0-UIr1 UI-E-EJ1 cDNA clone UI-E-EJ1-aje-b-23-0-UI 5' 0.42
13. AL117425 mRNA; cDNA DKFZp566L203 (from clone DKFZp566L203) 0.43
14. BQ430788 AGENCOURT_7776027 NIH_MGC_68 cDNA clone IMAGE:6024295 5' 0.44
15. AA594928 no40a05s1 NCI_CGAP_Pr23 cDNA clone IMAGE:1103120 3' 0.46
16. H05195 yl85f06r1 Soares infant brain 1NIB cDNA clone IMAGE:45005 5' 0.47
17. AK124841 cDNA FLJ42851 fis, clone BRHIP2005719 0.47
18. H05195 yl85f06r1 Soares infant brain 1NIB cDNA clone IMAGE:45005 5' 0.48
19. AL119769 DKFZp761E1224_r1 761 (synonym: hamy2) cDNA clone DKFZp761E1224 5' 0.54
20. AI094001 qa28a03s1 Soares_NhHMPu_S1 cDNA clone IMAGE:1688044 3' 0.54
21. AL133055 mRNA; cDNA DKFZp434J1015 (from clone DKFZp434J1015) 0.56
22. BX094154 Soares fetal liver spleen 1NFLS cDNA clone IMAGp998P17654 0.58
23. W67378 zd40b03r1 Soares_fetal_heart_NbHH19W cDNA clone IMAGE:343085 5' similar to SW:DHAM_HUMAN P05091 ALDEHYDE DEHYDROGENASE, MITOCHONDRIAL PRECURSOR; 0.58
24. BM829211 K-EST0102153 S9SNU601 cDNA clone S9SNU601-57-C10 5' 0.58
25. BM711907 UI-E-CL1-afc-i-20-0-UIr1 UI-E-CL1 cDNA clone UI-E-CL1-afc-i-20-0-UI 5' 0.59
26. BX088944 Soares_testis_NHT cDNA clone MAGp998J113516; IMAGE:1392490 0.72
27. BC033399 clone IMAGE:4829538 0.77
28. CB960582 AGENCOURT_13892014 NIH_MGC_147 cDNA clone IMAGE:30343321 5' 0.79
29. BC034566 clone IMAGE:4821877, mRNA 0.79
  1. SAM analysis was performed to identify the statistically significant differentially expressed genes. Genes that are common to both platforms are highlighted as Bold and Italics.
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