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Table 2 Quantitative summary of genetic associations with ABI that replicated, cross-validated, and passed FDR criterion

From: Investigating the complex genetic architecture of ankle-brachial index, a measure of peripheral arterial disease, in non-Hispanic whites

 

SNP Main Effects

SNP-Covariate Interactions

SNP-SNP Interactions

Number of tests

435

6926

91113

P < 0.10 on full sample

77

815

10308

FDR (< 0.30) on full sample

20

20

270

Cross Validation (on full sample)

5

52

404

Replication (P < 0.10 in both groups)

3

72

973

FDR and Cross-validation

5

14

79

FDR and Replication

2

4

36

Replication and Cross-validation

2

7

52

FDR and Cross-Validation and Replication

2

3

25

  1. FDR, False Discovery Rate
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BMC Medical Genomics

ISSN: 1755-8794

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