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Table 2 Representative upregulated genes (out of 259 total).

From: Microarray analysis in B cells among siblings with/without MS - role for transcription factor TCF2

Probe ID

Fold Change

Common

Genbank

Description

Upregulated genes

GE53598

5.88

TINAG

NM_014464

tubulointerstitial nephritis antigen, complete cds

GE59642

5.77

CXCL10

NM_001565

gamma-interferon inducible early response gene (with homology to platelet proteins)

GE57550

4.74

CRYM

NM_001888

mu-crystallin mRNA, complete cds

GE518123

4.27

IGLL1

NM_020070

immunoglobulin lambda-like polypeptide 1 (IGLL1), transcript variant 1, mRNA

GE58736

4.20

DACT1

NM_016651

dapper homolog 1, antagonist of beta-catenin (xenopus) (DACT1), mRNA

GE79033

4.15

CD9

NM_001769

CD9 antigen (p24) (CD9), mRNA

GE55346

3.57

LRRC16

NM_017640

leucine rich repeat containing 16 (LRRC16), mRNA

GE61239

3.50

SERPINB1

NM_030666

serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 1 (SERPINB1), mRNA

GE62781

3.50

MT1F

NM_005949

metallothionein 1F (functional) (MT1F), mRNA

GE87501

3.49

FXYD2

NM_001680

FXYD domain containing ion transport regulator 2 (FXYD2), transcript variant a, mRNA

GE61946

3.26

ARHGAP6

NM_001174

Rho GTPase activating protein 6 (ARHGAP6), transcript variant 2, mRNA

GE56932

3.22

EGLN3

NM_022073

egl nine homolog 3 (C. elegans) (EGLN3), mRNA

GE61093

3.18

ACTN1

NM_001102

actinin, alpha 1 (ACTN1), mRNA

GE87626

2.97

OSR2

NM_053001

odd-skipped-related 2A protein (OSR2), mRNA

GE59655

2.93

ATP1B1

NM_001677

ATPase, Na+/K+ transporting, beta 1 polypeptide (ATP1B1), mRNA

GE58575

2.91

PTPLA

NM_014241

protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a (PTPLA), mRNA

GE57767

2.84

COL9A3

NM_001853

collagen, type IX, alpha 3 (COL9A3), mRNA

GE57621

2.83

LGALS3BP

NM_005567

lectin, galactoside-binding, soluble, 3 binding protein (LGALS3BP), mRNA

GE81389

2.82

CCR6

NM_004367

chemokine (C-C motif) receptor 6 (CCR6), transcript variant 1, mRNA

GE79898

2.81

LYPLA3

NM_012320

lysophospholipase 3 (lysosomal phospholipase A2) (LYPLA3), mRNA

GE62292

2.79

CPXM

NM_019609

carboxypeptidase X (M14 family) (CPXM), mRNA

GE57547

2.66

TCN2

NM_000355

transcobalamin II; macrocytic anemia (TCN2), mRNA

GE81525

2.52

IFI27

NM_005532

ISG12 protein

GE79641

2.48

FUT4

NM_002033

fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) (FUT4), mRNA

GE81272

2.47

VIM

NM_003380

vimentin (VIM), mRNA

GE57737

2.45

ENPP2

NM_006209

autotaxin mRNA, complete cds

GE80150

2.38

ELF3

NM_004433

E74-like factor 3 (ets domain transcription factor, epithelial-specific) (ELF3), mRNA

GE58207

2.34

ENG

NM_000118

endoglin (Osler-Rendu-Weber syndrome 1) (ENG), mRNA

GE57048

2.33

CCR1

NM_001295

chemokine (C-C motif) receptor 1 (CCR1), mRNA

GE57883

2.28

SELL

NM_000655

selectin L (lymphocyte adhesion molecule 1) (SELL), mRNA

GE60214

2.27

NRGN

NM_006176

neurogranin (protein kinase C substrate, RC3) (NRGN), mRNA

GE498904

2.22

DACT1

NM_016651

dapper homolog 1, antagonist of beta-catenin (xenopus) (DACT1), mRNA

GE81340

2.17

PSTPIP1

NM_003978

proline-serine-threonine phosphatase interacting protein 1 (PSTPIP1), mRNA

GE58931

2.16

TCF8

U12170

zinc finger homeodomain protein mRNA, complete cds

GE61464

2.15

SERPINB9

NM_004155

serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9 (SERPINB9), mRNA

GE82947

2.12

SNX22

NM_024798

sorting nexin 22 (SNX22), mRNA

GE60134

2.09

UPP1

NM_003364

uridine phosphorylase (UP), transcript variant 1, mRNA

GE54152

2.07

APOL1

NM_003661

apolipoprotein L, 1 (APOL1), transcript variant 1, mRNA

GE56786

2.02

DUSP4

NM_001394

dual specificity phosphatase 4 (DUSP4), transcript variant 1, mRNA

GE54528

2.02

TNFSF12;

NM_003809

tumor necrosis factor (ligand) superfamily, member 12 (TNFSF12), transcript variant 1, mRNA

GE61789

2.02

TDE2L

NM_178865

tumor differentially expressed protein 2 (TDE2), mRNA

GE61399

2.01

LLT1

NM_013269

lectin-like NK cell receptor (LLT1), mRNA

  1. Fold change = diseased/normal