Advertisement
Table 2 Top coregulated clusters of genes
| Human cluster | Rat cluster | ||||
|---|---|---|---|---|---|
| Gene Symbol | Gene Description | t* | q** | t* | q** |
| DSG1 | desmoglein 1 | 6.5 | 0 | 12.8 | 0 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 6.8 | 0 | 5.1 | 0 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 | 5.2 | 0.0002 | 9.5 | 0 |
| SC4MOL | sterol-C4-methyl oxidase-like | 4.1 | 0.0025 | 9.2 | 0 |
| FAM46B | family with sequence similarity 46, member B | 2.4 | 0.0896 | 10.2 | 0 |
| CRABP2 | cellular retinoic acid binding 2 | 4.0 | 0.0029 | 12.6 | 0 |
| CBR3 | carbonyl reductase 3 | 5.2 | 0.0002 | 6.5 | 0 |
| SLURP1 | secreted LY6/PLAUR domain | 4.4 | 0.0014 | 9.1 | 0 |
| ATP6V1D | ATPase, H+ transporting, lysosomal, V1 subunit D | 4.4 | 0.0011 | 9.5 | 0 |
| KLF4 | Kruppel-like factor 4 | 4.3 | 0.0016 | 7.5 | 0 |
| GPT2 | glutamic pyruvate transaminase | 3.3 | 0.0175 | 8.7 | 0 |
| CLIC3 | chloride intracellular channel 3 | 2.8 | 0.0481 | 9.2 | 0 |
| MAL2 | T-cell differentiation protein 2 | 4.2 | 0.002 | 7.9 | 0 |
| S100A10 | S100 calcium binding protein A10 | 3.7 | 0.0067 | 9.1 | 0 |
| FLJ12151 | hypothetical protein FLJ12151 | 4.7 | 0.0006 | 6.4 | 0 |
| HMGCR | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | 4.3 | 0.0016 | 5.7 | 0 |
| MAFB | musculoaponeurotic fibrosarcoma homolog B | 3.7 | 0.0071 | 5.7 | 0 |
| RAB10 | RAB10, member RAS oncogene family | 3.5 | 0.0119 | 8.7 | 0 |
| SERPINB2 | serine proteinase inhibitor, clade B 2 | 3.4 | 0.0137 | 7.9 | 0 |
| SQLE | Squalene epoxidase | 2.8 | 0.0471 | 8.4 | 0 |
| AVPI1 | arginine vasopressin-induced 1 | 4.4 | 0.0012 | 6.8 | 0 |
| AIM1L | absent in melanoma 1-like | 2.6 | 0.0625 | 8.8 | 0 |
| BNIP3 | BCL2/adenovirus E1B 19 kDa interacting protein 3 | 6.3 | 0 | 5.2 | 0 |
| BZW1 | basic leucine zipper and W2 domains 1 | 3.9 | 0.0038 | 6.3 | 0 |
| LOC58489 | hypothetical protein | 2.9 | 0.0386 | 8.6 | 0 |
| AACS | acetoacetyl-CoA synthetase | 4.1 | 0.0024 | 4.7 | 0 |
| MGC13102 | hypothetical protein MGC13102 | 3.7 | 0.0068 | 7.6 | 0 |
| ETF1 | eukaryotic translation termination factor 1 | 2.8 | 0.0438 | 8.0 | 0 |
| C4.4A | GPI-anchored metastasis-associated protein homolog | 3.0 | 0.0327 | 9.2 | 0 |
| HMOX1 | heme oxygenase 1 | 5.5 | 0.0002 | 5.1 | 0 |
| KCTD11 | K+ channel tetramerisation domain containing 11 | 4.7 | 0.0006 | 3.8 | 0 |
| CDK7 | cyclin-dependent kinase 7 | 5.9 | 0.0002 | 2.4 | 0.02 |
| JUNB | jun B proto-oncogene | 3.5 | 0.0113 | 5.7 | 0 |
| RIOK3 | RIO kinase 3 | 4.7 | 0.0006 | 4.6 | 0 |
| ME1 | malic enzyme 1 | 4.6 | 0.0007 | 4.6 | 0 |
| YWHAZ | tyrosine 3-monooxygenase activation protein, zeta | 2.5 | 0.0779 | 9.0 | 0 |
