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Table 2 Top coregulated clusters of genes

From: Molecular analysis of the vaginal response to estrogens in the ovariectomized rat and postmenopausal woman

   Human cluster Rat cluster
Gene Symbol Gene Description t* q** t* q**
DSG1 desmoglein 1 6.5 0 12.8 0
GADD45A growth arrest and DNA-damage-inducible, alpha 6.8 0 5.1 0
HMGCS1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 5.2 0.0002 9.5 0
SC4MOL sterol-C4-methyl oxidase-like 4.1 0.0025 9.2 0
FAM46B family with sequence similarity 46, member B 2.4 0.0896 10.2 0
CRABP2 cellular retinoic acid binding 2 4.0 0.0029 12.6 0
CBR3 carbonyl reductase 3 5.2 0.0002 6.5 0
SLURP1 secreted LY6/PLAUR domain 4.4 0.0014 9.1 0
ATP6V1D ATPase, H+ transporting, lysosomal, V1 subunit D 4.4 0.0011 9.5 0
KLF4 Kruppel-like factor 4 4.3 0.0016 7.5 0
GPT2 glutamic pyruvate transaminase 3.3 0.0175 8.7 0
CLIC3 chloride intracellular channel 3 2.8 0.0481 9.2 0
MAL2 T-cell differentiation protein 2 4.2 0.002 7.9 0
S100A10 S100 calcium binding protein A10 3.7 0.0067 9.1 0
FLJ12151 hypothetical protein FLJ12151 4.7 0.0006 6.4 0
HMGCR 3-hydroxy-3-methylglutaryl-Coenzyme A reductase 4.3 0.0016 5.7 0
MAFB musculoaponeurotic fibrosarcoma homolog B 3.7 0.0071 5.7 0
RAB10 RAB10, member RAS oncogene family 3.5 0.0119 8.7 0
SERPINB2 serine proteinase inhibitor, clade B 2 3.4 0.0137 7.9 0
SQLE Squalene epoxidase 2.8 0.0471 8.4 0
AVPI1 arginine vasopressin-induced 1 4.4 0.0012 6.8 0
AIM1L absent in melanoma 1-like 2.6 0.0625 8.8 0
BNIP3 BCL2/adenovirus E1B 19 kDa interacting protein 3 6.3 0 5.2 0
BZW1 basic leucine zipper and W2 domains 1 3.9 0.0038 6.3 0
LOC58489 hypothetical protein 2.9 0.0386 8.6 0
AACS acetoacetyl-CoA synthetase 4.1 0.0024 4.7 0
MGC13102 hypothetical protein MGC13102 3.7 0.0068 7.6 0
ETF1 eukaryotic translation termination factor 1 2.8 0.0438 8.0 0
C4.4A GPI-anchored metastasis-associated protein homolog 3.0 0.0327 9.2 0
HMOX1 heme oxygenase 1 5.5 0.0002 5.1 0
KCTD11 K+ channel tetramerisation domain containing 11 4.7 0.0006 3.8 0
CDK7 cyclin-dependent kinase 7 5.9 0.0002 2.4 0.02
JUNB jun B proto-oncogene 3.5 0.0113 5.7 0
RIOK3 RIO kinase 3 4.7 0.0006 4.6 0
ME1 malic enzyme 1 4.6 0.0007 4.6 0
YWHAZ tyrosine 3-monooxygenase activation protein, zeta 2.5 0.0779 9.0 0
  1. t* Average t-statistic
  2. q** Average q-value