Table 3 Top coregulated clusters of genes
Human cluster | Rat cluster | ||||
|---|---|---|---|---|---|
Gene Symbol | Gene Description | t* | q** | t* | q** |
TXNIP | thioredoxin interacting protein | -5.5 | 0.0002 | -12.5 | 0 |
RBP1 | retinol binding protein 1, cellular | -4.2 | 0.0021 | -15.1 | 0 |
IGFBP3 | insulin-like growth factor binding protein 3 | -4.6 | 0.0007 | -10.0 | 0 |
IFITM3 | interferon induced transmembrane protein 3 (1–8 U) | -5.2 | 0.0002 | -9.0 | 0 |
DHRS8 | dehydrogenase/reductase (SDR family) member 8 | -5.4 | 0.0002 | -5.6 | 0 |
LDHB | lactate dehydrogenase B | -4.6 | 0.0006 | -6.1 | 0 |
LAPTM4B | lysosomal associated protein transmembrane 4 beta | -4.5 | 0.0008 | -8.3 | 0 |
MUC1 | mucin 1, transmembrane | -5.7 | 0.0002 | -5.2 | 0 |
SFRP2 | secreted frizzled-related protein 2 | -5.4 | 0.0002 | -5.8 | 0 |
IFITM1 | interferon induced transmembrane protein 1 (9–27) | -4.2 | 0.0019 | -6.8 | 0 |
CD74 | CD74 antigen | -4.3 | 0.0015 | -8.2 | 0 |
LR8 | LR8 protein | -3.6 | 0.0076 | -7.6 | 0 |
B2M | beta-2-microglobulin | -4.1 | 0.0025 | -8.0 | 0 |
PPP1R1B | protein phosphatase 1, regulatory (inhibitor) subunit 1B | -4.8 | 0.0006 | -6.1 | 0 |
PRKACB | protein kinase, cAMP-dependent, catalytic, beta | -5.2 | 0.0003 | -4.2 | 0 |
TSPAN3 | tetraspanin 3 | -4.4 | 0.0014 | -6.5 | 0 |
PROM1 | prominin 1 | -2.8 | 0.0452 | -9.0 | 0 |
TMC4 | transmembrane channel-like 4 | -3.8 | 0.0045 | -8.0 | 0 |
ITM2C | integral membrane protein 2C | -3.0 | 0.0343 | -8.0 | 0 |
DHRS3 | dehydrogenase/reductase (SDR family) member 3 | -3.6 | 0.0079 | -5.9 | 0 |
ITM2B | integral membrane protein 2B | -2.5 | 0.0778 | -9.6 | 0 |
VIM | vimentin | -2.7 | 0.0503 | -9.6 | 0 |
NPC2 | Niemann-Pick disease, type C2 | -4.0 | 0.0029 | -6.5 | 0 |
AXL | AXL receptor tyrosine kinase | -4.4 | 0.0012 | -4.9 | 0 |
HLA-DRA | major histocompatibility complex, class II, DR alpha | -3.3 | 0.0153 | -8.5 | 0 |
EEF1A1 | Eukaryotic translation elongation factor 1 alpha 1 | -4.1 | 0.0023 | -5.1 | 0 |
FOXQ1 | forkhead box Q1 | -3.5 | 0.0116 | -6.1 | 0 |
IFNGR1 | interferon gamma receptor 1 | -2.5 | 0.0745 | -8.5 | 0 |
IGFBP7 | insulin-like growth factor binding protein 7 | -3.4 | 0.0138 | -7.2 | 0 |
RNASET2 | ribonuclease T2 | -3.0 | 0.032 | -7.4 | 0 |
SAT | spermidine/spermine N1-acetyltransferase | -3.7 | 0.0073 | -7.6 | 0 |
BHLHB3 | basic helix-loop-helix domain containing, class B, 3 | -5.8 | 0.0002 | -2.3 | 0.04 |
SELENBP1 | selenium binding protein 1 | -4.0 | 0.0033 | -4.8 | 0 |
C11orf8 | chromosome 11 open reading frame 8 | -5.0 | 0.0004 | -3.6 | 0 |
LSP1 | lymphocyte-specific protein 1 | -4.9 | 0.0004 | -2.9 | 0 |
KRT19 | keratin 19 | -3.3 | 0.0 | -10.1 | 0 |