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Table 1 List of transcripts regulated by rapamycin (Ingenuity classification)

From: An approach to analyse the specific impact of rapamycin on mRNA-ribosome association

Inflammation
Upregulated Downregulated
apobec3f lst1 adra1a epha4 il1rn ptpn22 tlr7
blnk mdm2 adra2c f9 irf2 ptprc zeb1
cald1 oas1 alpp fas itgb3 ptprz1  
cmklr1 parvg bcl11a faslg klf2 rbl2  
ctla4 pdgfc bcl2l1 fcgr2a lama3 rbm15  
cxcr4 rag2 cast folr1 lilra2 rbpj  
cyp3a4 rela cd28 fyb mll rel  
fyn sat1 cd36 gal mpo satb1  
hla-g tcf12 clec1b gap43 pcgf2 siglec8  
ifih1 tfap4 cul4a gnrh1 pla2g6 smpd1  
ifna2 thbs1 cxcl11 gnrhr plcg1 spn  
il16 tlr7 cyp3a4 hal-dqb1 prdm16 syk  
il28b unc119 ddl1 hck pscdbp thra  
itga4 vtcn1 dok2 ifne1 ptgs2 thrb  
Cell growth and proliferation
Upregulated Downregulated
adam12 mdm2 adra1a dok2 gnrh1 olig2 rffl
blnk pappa bcl2l1 f12 hck p53aip1 sec14l2
cdc2l5 rag2 ccl27 fas hmga2 pcgf2 syk
ctla4 rela cd28 faslg irf2 pdgfa tfr2
cxcr4 s100b cdca7 fbxo2 itgb3 piwil1 tgif1
erbb3 ss18 clca2 fcer2 klf2 pla2g6 thra
fyn tcf12 cltc fgf18 lzts1 ptgs2 thrb
hla-g thbs1 csh2 folr1 mdm4 ptk2 tnfsf15
igf1r unc119 cyp2c9 foxo1 mll ptpn22 zfn10
il28b vtcn1 dcc gal nab2 ptpra  
itga4   ddx17 gap43 nos1 ptprc  
lst1   dll1 glmn nov rbl2  
Cell death
Upregulated Downregulated
blnk itga2 abcd2 dll1 hmga2 p53aip1 rbm17
cdk6 mdm2 acvr1b eraf ifne1 pigt rel
ctla4 rag2 adora2a faf1 il1rn piwil1 satb1
cul3 rela atrx fas irf2 pla2g6 serpinb4
cxcr4 rnase1 atxn3 faslg itgb3 pou4f1 siglec8
cyp2e1 sgpp1 bcl2l1 fcer2 klf2 ppp1r9b smpd1
cyp3a4 tfap4 bircabp foxo1 klra1 ppp2r1b spn
erbb3 thbs1 cast gal lrp5 prdm2 stk4
erg traf4 ccl27 gimap5 mdm4 ptgs2 syk
fyn zmym2 cd28 gng2 mll ptk2 thra
hla-g   cdk6 gria2 mpo ptpn22 tnfsf15
ifih1   cyp2e1 grik2 nol3 ptprc traf5
ifna2   cyp3a4 grm1 nos1 ptprz1 trps1
igf1r   dcc hint1 nrtn rbl2 znf10
Phagocytosis
Upregulated Downregulated    
   cd36 klf2    
   fas mpo    
   fcgr2a pla2g6    
   hck syk    
   itgb3     
  1. The 1160 mRNAs identified in the microarray screen (as listed in Additional File 2) were plotted onto biological networks using the Ingenuity Pathway Analysis Software package. Those whose protein products are involved in inflammation, phagocytosis, cell growth/proliferation and cell death are listed.