Table 2 Types of curated arsenic-gene interactions
Arsenic-to-Gene Molecular Interactions | Genes1 |
|---|---|
mRNA up-regulated | 810 |
mRNA down-regulated | 652 |
Protein up-regulated | 97 |
mRNA/protein altered2 | 82 |
Protein activity | 78 |
Protein down-regulated | 49 |
Protein phosphorylation | 39 |
Protein cleavage/degradation | 14 |
Protein localization | 14 |
Protein secretion | 8 |
Promoter methylation | 7 |
Protein metabolism | 6 |
mRNA/protein stabilization | 4 |
Gene mutagenesis | 4 |
Gene-to-Arsenic Molecular Interactions | Genes 1 |
Arsenic resistance/susceptibility | 43 |
Arsenic transport | 5 |
Arsenic metabolism | 5 |
Protein binds arsenic | 5 |