Skip to main content
Figure 1 | BMC Medical Genomics

Figure 1

From: Multiplex ligation-dependent probe amplification for genetic screening in autism spectrum disorders: Efficient identification of known microduplications and identification of a novel microduplication in ASMT

Figure 1

Chromosome 15q11-q13 duplications in four families. A. Schematic representation of the region, highlighting the extent of the duplications in the four families (blue lines), the localization of the MLPA probes (red triangles) and FISH probes (yellow ovals) used, and the genes within the interval along with their orientation (green arrows). B. MLPA peak ratio for 15q11-13 (red and green) and control (blue) MLPA test probes in Family 1 individuals AU010604 (left) and AU010602 (right). Red, probes with peak ratios > 1.3; green, probes with peak ratios <= 1.3. In the left panel, the green rectangle with a peak ratio of ~1 corresponds to APBA2. C. Segregation of the duplications in the four families.

Back to article page

BMC Medical Genomics

ISSN: 1755-8794

Contact us