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Table 1 The protein expression levels of UBA1 and UBA7 in the tumour and normal tissue of adenocarcinoma and squamous cell carcinoma patients obtained using Western analysis and gene expression (GE) microarrays

From: Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients

  UBA1 UBA7
  Western GE probe 1 Western GE probe 1 GE probe 2
Tissue typea Median
[range]
Median
[range]
SCC 0.72
[0.29 0.91]
1097
[827 1410]
0.16
[0.13 0.27]
71
[54 88]
84
[67 95]
Normal 1.3
[0.81 2.8]
1723
[1037 1815]
0.74
[0.50 1.7]
131
[108 170]
194
[147 253]
p-valueb 0.02 0.03 0.01 0.00086 0.00018
AC 1.1
[0.70 1.2]
1326
[658 1656]
0.50
[0.15 0.62]
104
[72 160]
122
[68 228]
Normal 1.1
[0.24 1.9]
1162
[932 1601]
0.46
[0.11 0.95]
137
[119 221]
203
[162 406]
p-valueb 0.80 0.42 0.79 0.01 0.003
  1. aAC, adenocarcinoma; SCC, squamous cell carcinoma
  2. bp-value was calculated using two-sided t-test