Table 1 The protein expression levels of UBA1 and UBA7 in the tumour and normal tissue of adenocarcinoma and squamous cell carcinoma patients obtained using Western analysis and gene expression (GE) microarrays
From: Pathways affected by asbestos exposure in normal and tumour tissue of lung cancer patients
| Â | UBA1 | UBA7 | |||
|---|---|---|---|---|---|
| Â | Western | GE probe 1 | Western | GE probe 1 | GE probe 2 |
Tissue typea | Median [range] | Median [range] | |||
SCC | 0.72 [0.29 0.91] | 1097 [827 1410] | 0.16 [0.13 0.27] | 71 [54 88] | 84 [67 95] |
Normal | 1.3 [0.81 2.8] | 1723 [1037 1815] | 0.74 [0.50 1.7] | 131 [108 170] | 194 [147 253] |
p-valueb | 0.02 | 0.03 | 0.01 | 0.00086 | 0.00018 |
AC | 1.1 [0.70 1.2] | 1326 [658 1656] | 0.50 [0.15 0.62] | 104 [72 160] | 122 [68 228] |
Normal | 1.1 [0.24 1.9] | 1162 [932 1601] | 0.46 [0.11 0.95] | 137 [119 221] | 203 [162 406] |
p-valueb | 0.80 | 0.42 | 0.79 | 0.01 | 0.003 |