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Table 4 Selected genes of the NRF2, cytokine response and NF-kB signaling pathways upregulated in patients with unfavorable DFS and OS

From: Carboplatin-induced gene expression changes in vitroare prognostic of survival in epithelial ovarian cancer

PATHWAY PATHWAY P VALUE * GENE GENE P VALUE**
Oxidative stress response via Nrf2 < 0.0001 MAFF < 0.0001
   NRF2 (NFE2L2) < 0.0001
   CRYZ < 0.001
   CREB1 0.015
Cytokine and Inflammatory Response < 0.0001 IL-6 0.005
   IL-8 0.013
   IL-15 0.0005
NF-kB signaling pathway 0.0002 NF-kB1 < 0.0001
   IL1-R1 0.003
   CHUK 0.002
   RELA 0.005
  1. * By Functional Class Scoring Method
  2. ** By t-test