Skip to main content

Table 3 List of genes selected from microarrays analysis comparing normal mucosa matched tumour colon tissue. The different expression in tumoural tissue was showed.

From: Promoter methylation correlates with reduced NDRG2expression in advanced colon tumour

Function/category Gene Accession no. Microarray Data Gene description
    P value Expression  
Insulin Receptor Signaling SGK1 NM_005627.1 0.059 down Serum glucocorticoid regulated kinase (SGK)
Transport CLCA4 NM_012128.2 0.052 down chloride channel, calcium activated, family member 4
Transport SLC26A3/DRA NM_000111.1 0.044 down solute carrier family 26, member 3 (SLC26A3)
Transport AQP8 NM_001169.1 0.052 down aquaporin 8
Transport SCNN1B NM_000336.1 0.046 down sodium channel, nonvoltage-gated 1, beta (S. Liddle)
Transport (ATP binding) ABCA8 NM_007168.1 0.040 down ATP-binding cassette, sub-family A (ABC1), member 8
Protein transport STX12 AI816243 0.051 down syntaxin 12
Receptor activity (mineralcorticoid) NR3C2 NM_000901.1 0.049 down nuclear receptor subfamily 3, group C, member 2
Cell cycle (proliferation) MXI1 NM_005962.1 0.053 down MAX-interacting protein 1 (MXI1)
Cell cycle (differentiation) NDRG2 NM_016250.1 0.039 down N-myc downstream-regulated gene 2
Prostaglandin metabolism HPGD J05594.1 0.050 down hydroxyprostaglandin dehydrogenase 15-(NAD)
Prostaglandin and leukotriene Metabolism PRDX6 NM_004905.1 0.050 down peroxidase, acidic calcium-independent phospholipase A2
Signal tansduction SGK2 NM_016276.3 0.038 down serumglucocorticoid regulated kinase (SGK)
Transcription factors FOXM1 NM_021953.1 0.046 up forkhead box M1 (FOXM1)
Transcription factors GTF2IRD1 NM_016328.1 0.046 up GTF2I repeat domain-containing 1 (GTF2IRD1)
Transcription factor SOX9 NM_000346.1 0.045 up Sex determining region Y-box 9
ATP-binding/proteins folding HSPH1 BG403660 0.043 up heat shock 105 kD (HSP105B)
Transport solute carrier SLC12A2 NM_001046 0.048 up solute carrier family 12
Cell cycle (proliferation) TPX2 NM_012112.1 0.044 up restricted expressed proliferation associated protein
Cell cycle (progression) UBE2C NM_007019.1 0.050 up ubiquitin carrier protein E2-C (UBCH10)
Cell cycle (proliferation) CSE1L/CAS NM_001316 0.052 up CSE1 chromosome segregation 1-like (yeast)
Signal Transduction CCNB1 Hs.23960 0.048 up cyclin B1
Focal adhesion NEBL NM_006393.1 0.038 up nebulette protein (NEBL, actin-binding Z-disc protein)
Replication and repair RFC3 BC000149 0.049 up replication factor C (activator 1) 3 (38 kD)