From: Promoter methylation correlates with reduced NDRG2expression in advanced colon tumour
Age (yrs): | Â | Â | Â |
---|---|---|---|
 | Number of CRC with NDRG2 methylation (%) | Number of CRC without NDRG2 methylation (%) | p value |
   Age <50 | 4 (13.3) | 5 (16.6) | ns |
   Age >50 | 4 (13.3) | 17 (56.6) |  |
Gender | Â | Â | Â |
   Male | 4 (26.7) | 11 (73.3) | ns |
   Female | 4 (26.7) | 11 (73.3) |  |
CRC: | Â | Â | Â |
   Familiar | 2 (25.0) | 6 (75.0) | ns |
   Sporadic | 6 (27.3) | 16 (72.7) |  |
Tumour location: | Â | Â | Â |
   Proximal colon | 2 (22.2) | 7 (77.7) | ns |
   Distal colon | 6 (28.6) | 15 (71.4) |  |
AJCC stage: | Â | Â | Â |
0 | 0 | 1 (4.8) | ns* |
I | 1 (12.5) | 2 (9.5) | Â |
IIa | 1 (12.5) | 7 (33.3) | Â |
IIIb | 0 | 3 (14.3) | Â |
IV | 6 (75.0) | 8 (38.1) | < 0,05^ |
MSI status 1 | Â | Â | Â |
   High | 1 (25.0) | 3 (75.0) | ns |
   Low | 1 (33.4) | 2 (66.7) |  |
   Stable | 6 (27.3) | 17 (72.7) |  |