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Figure 4 | BMC Medical Genomics

Figure 4

From: Impact of sample acquisition and linear amplification on gene expression profiling of lung adenocarcinoma: laser capture micro-dissection cell-sampling versus bulk tissue-sampling

Figure 4

Overlap of identified probesets with cancer to normal differential expression in the bulk, LCM, and linear amplified bulk datasets. The number of upregulated probesets (a) identified is consistent between datasets, with the closest agreement between bulk and linear amplified bulk samples. For down-regulated probesets (b), there remains a tight association between bulk and linear amplified bulk samples. In the LCM samples the number of observed down-regulated probesets is substantially higher than that observed in either the bulk or linear amplified bulk samples.

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BMC Medical Genomics

ISSN: 1755-8794

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