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Table 1 Genes significantly changed by at least 2-fold difference in pterygium (p < 0.05)

From: Distinct gene subsets in pterygia formation and recurrence: dissecting complex biological phenomenon using genome wide expression data

Up-regulated in pterygium

Probe ID

Gene

symbol

Genbank accession

Fold change

209125_at

KRT6A

J00269

6.399

205009_at

TFF1

NM_003225

5.671

210297_s_at

MSMB

U22178

4.175

211719_x_at

FN1

BC005858

4.112

212464_s_at

FN1

X02761

3.939

216442_x_at

FN1

AK026737

3.827

207811_at

KRT12

NM_000223

3.781

210495_x_at

FN1

AF130095

3.738

207430_s_at

MSMB

NM_002443

3.732

202310_s_at

COL1A1

K01228

3.635

216379_x_at

 

AK000168

3.475

209771_x_at

CD24

AA761181

3.42

218990_s_at

SPRR3

NM_005416

3.401

201884_at

CEACAM5

NM_004363

3.287

214385_s_at

MUC5B

AI521646

3.244

202404_s_at

COL1A2

NM_000089

3.149

205064_at

SPRR1B

NM_003125

3.053

204777_s_at

MAL

NM_002371

3.043

211161_s_at

 

AF130082

2.937

219087_at

ASPN

NM_017680

2.903

214303_x_at

MUC5AC

AW192795

2.897

209047_at

AQP1

AL518391

2.773

213796_at

SPRR1A

AI923984

2.772

205694_at

TYRP1

NM_000550

2.736

214580_x_at

KRT6A

AL569511

2.645

217272_s_at

SERPINB13

AJ001698

2.545

218963_s_at

KRT23

NM_015515

2.506

218353_at

RGS5

NM_025226

2.476

205547_s_at

TAGLN

NM_003186

2.467

217388_s_at

KYNU

D55639

2.441

201438_at

COL6A3

NM_004369

2.423

203477_at

COL15A1

NM_001855

2.374

203980_at

FABP4

NM_001442

2.364

202311_s_at

COL1A1

AI743621

2.334

215076_s_at

COL3A1

AU144167

2.331

213975_s_at

LYZ

AV711904

2.322

209071_s_at

RGS5

AF159570

2.275

210809_s_at

POSTN

D13665

2.261

202878_s_at

C1QR1

NM_012072

2.242

217528_at

CLCA2

BF003134

2.226

204682_at

LTBP2

NM_000428

2.21

212190_at

SERPINE2

AL541302

2.201

219410_at

FLJ10134

NM_018004

2.171

209848_s_at

SILV

U01874

2.15

204351_at

S100P

NM_005980

2.114

204971_at

CSTA

NM_005213

2.092

206427_s_at

MLANA

U06654

2.088

202917_s_at

S100A8

NM_002964

2.084

203382_s_at

APOE

NM_000041

2.081

211980_at

COL4A1

AI922605

2.077

200665_s_at

SPARC

NM_003118

2.071

201667_at

GJA1

NM_000165

2.06

218723_s_at

RGC32

NM_014059

2.056

203691_at

PI3

NM_002638

2.05

206276_at

LY6D

NM_003695

2.04

219412_at

RAB38

NM_022337

2.04

208982_at

PECAM1

AW574504

2.029

203504_s_at

ABCA1

NM_005502

2.026

201852_x_at

COL3A1

AI813758

2.01

203570_at

LOXL1

NM_005576

2.01

Down-regulated in pterygium

Probe ID

Gene

Genbank accession

Fold change

217232_x_at

HBB

AF059180

0.5

208078_s_at

TCF8

NM_030751

0.499

201842_s_at

EFEMP1

AI826799

0.496

201008_s_at

TXNIP

AA812232

0.495

215176_x_at

 

AW404894

0.494

206391_at

RARRES1

NM_002888

0.494

212225_at

SUI1

AL516854

0.492

201505_at

LAMB1

NM_002291

0.488

205979_at

SCGB2A1

NM_002407

0.487

209278_s_at

TFPI2

L27624

0.482

211003_x_at

TGM2

BC003551

0.479

211573_x_at

TGM2

M98478

0.479

202431_s_at

MYC

NM_002467

0.475

213831_at

HLA-DQA1

X00452

0.47

210095_s_at

IGFBP3

M31159

0.465

206392_s_at

RARRES1

NM_002888

0.46

211651_s_at

LAMB1

M20206

0.455

201843_s_at

EFEMP1

NM_004105

0.443

202081_at

IER2

NM_004907

0.439

202340_x_at

NR4A1

NM_002135

0.435

200664_s_at

DNAJB1

BG537255

0.435

209116_x_at

HBB

M25079

0.431

215723_s_at

PLD1

AJ276230

0.43

205910_s_at

CEL

NM_001807

0.417

219759_at

LRAP

NM_022350

0.416

204286_s_at

PMAIP1

NM_021127

0.406

206424_at

CYP26A1

NM_000783

0.403

206393_at

TNNI2

NM_003282

0.396

201466_s_at

JUN

NM_002228

0.388

201464_x_at

JUN

BG491844

0.368

212143_s_at

IGFBP3

BF340228

0.359

201473_at

JUNB

NM_002229

0.356

217022_s_at

MGC27165

S55735

0.355

201236_s_at

BTG2

NM_006763

0.342

204285_s_at

PMAIP1

AI857639

0.301

201041_s_at

DUSP1

NM_004417

0.296

201044_x_at

DUSP1

AA530892

0.265

204622_x_at

NR4A2

NM_006186

0.22

201694_s_at

EGR1

NM_001964

0.215

204621_s_at

NR4A2

AI935096

0.192

213674_x_at

IGHM

AI858004

0.188

216248_s_at

NR4A2

S77154

0.17

202768_at

FOSB

NM_006732

0.167

202672_s_at

ATF3

NM_001674

0.159

209189_at

FOS

BC004490

0.072