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Table 1 Genes significantly changed by at least 2-fold difference in pterygium (p < 0.05)

From: Distinct gene subsets in pterygia formation and recurrence: dissecting complex biological phenomenon using genome wide expression data

Up-regulated in pterygium
Probe ID Gene
symbol
Genbank accession Fold change
209125_at KRT6A J00269 6.399
205009_at TFF1 NM_003225 5.671
210297_s_at MSMB U22178 4.175
211719_x_at FN1 BC005858 4.112
212464_s_at FN1 X02761 3.939
216442_x_at FN1 AK026737 3.827
207811_at KRT12 NM_000223 3.781
210495_x_at FN1 AF130095 3.738
207430_s_at MSMB NM_002443 3.732
202310_s_at COL1A1 K01228 3.635
216379_x_at   AK000168 3.475
209771_x_at CD24 AA761181 3.42
218990_s_at SPRR3 NM_005416 3.401
201884_at CEACAM5 NM_004363 3.287
214385_s_at MUC5B AI521646 3.244
202404_s_at COL1A2 NM_000089 3.149
205064_at SPRR1B NM_003125 3.053
204777_s_at MAL NM_002371 3.043
211161_s_at   AF130082 2.937
219087_at ASPN NM_017680 2.903
214303_x_at MUC5AC AW192795 2.897
209047_at AQP1 AL518391 2.773
213796_at SPRR1A AI923984 2.772
205694_at TYRP1 NM_000550 2.736
214580_x_at KRT6A AL569511 2.645
217272_s_at SERPINB13 AJ001698 2.545
218963_s_at KRT23 NM_015515 2.506
218353_at RGS5 NM_025226 2.476
205547_s_at TAGLN NM_003186 2.467
217388_s_at KYNU D55639 2.441
201438_at COL6A3 NM_004369 2.423
203477_at COL15A1 NM_001855 2.374
203980_at FABP4 NM_001442 2.364
202311_s_at COL1A1 AI743621 2.334
215076_s_at COL3A1 AU144167 2.331
213975_s_at LYZ AV711904 2.322
209071_s_at RGS5 AF159570 2.275
210809_s_at POSTN D13665 2.261
202878_s_at C1QR1 NM_012072 2.242
217528_at CLCA2 BF003134 2.226
204682_at LTBP2 NM_000428 2.21
212190_at SERPINE2 AL541302 2.201
219410_at FLJ10134 NM_018004 2.171
209848_s_at SILV U01874 2.15
204351_at S100P NM_005980 2.114
204971_at CSTA NM_005213 2.092
206427_s_at MLANA U06654 2.088
202917_s_at S100A8 NM_002964 2.084
203382_s_at APOE NM_000041 2.081
211980_at COL4A1 AI922605 2.077
200665_s_at SPARC NM_003118 2.071
201667_at GJA1 NM_000165 2.06
218723_s_at RGC32 NM_014059 2.056
203691_at PI3 NM_002638 2.05
206276_at LY6D NM_003695 2.04
219412_at RAB38 NM_022337 2.04
208982_at PECAM1 AW574504 2.029
203504_s_at ABCA1 NM_005502 2.026
201852_x_at COL3A1 AI813758 2.01
203570_at LOXL1 NM_005576 2.01
Down-regulated in pterygium
Probe ID Gene Genbank accession Fold change
217232_x_at HBB AF059180 0.5
208078_s_at TCF8 NM_030751 0.499
201842_s_at EFEMP1 AI826799 0.496
201008_s_at TXNIP AA812232 0.495
215176_x_at   AW404894 0.494
206391_at RARRES1 NM_002888 0.494
212225_at SUI1 AL516854 0.492
201505_at LAMB1 NM_002291 0.488
205979_at SCGB2A1 NM_002407 0.487
209278_s_at TFPI2 L27624 0.482
211003_x_at TGM2 BC003551 0.479
211573_x_at TGM2 M98478 0.479
202431_s_at MYC NM_002467 0.475
213831_at HLA-DQA1 X00452 0.47
210095_s_at IGFBP3 M31159 0.465
206392_s_at RARRES1 NM_002888 0.46
211651_s_at LAMB1 M20206 0.455
201843_s_at EFEMP1 NM_004105 0.443
202081_at IER2 NM_004907 0.439
202340_x_at NR4A1 NM_002135 0.435
200664_s_at DNAJB1 BG537255 0.435
209116_x_at HBB M25079 0.431
215723_s_at PLD1 AJ276230 0.43
205910_s_at CEL NM_001807 0.417
219759_at LRAP NM_022350 0.416
204286_s_at PMAIP1 NM_021127 0.406
206424_at CYP26A1 NM_000783 0.403
206393_at TNNI2 NM_003282 0.396
201466_s_at JUN NM_002228 0.388
201464_x_at JUN BG491844 0.368
212143_s_at IGFBP3 BF340228 0.359
201473_at JUNB NM_002229 0.356
217022_s_at MGC27165 S55735 0.355
201236_s_at BTG2 NM_006763 0.342
204285_s_at PMAIP1 AI857639 0.301
201041_s_at DUSP1 NM_004417 0.296
201044_x_at DUSP1 AA530892 0.265
204622_x_at NR4A2 NM_006186 0.22
201694_s_at EGR1 NM_001964 0.215
204621_s_at NR4A2 AI935096 0.192
213674_x_at IGHM AI858004 0.188
216248_s_at NR4A2 S77154 0.17
202768_at FOSB NM_006732 0.167
202672_s_at ATF3 NM_001674 0.159
209189_at FOS BC004490 0.072