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Table 8 AM genes mapping in frequently mutated genome regions with concordant transcriptome and proteome alterations in cancer

From: The apoptotic machinery as a biological complex system: analysis of its omics and evolution, identification of candidate genes for fourteen major types of cancer, and experimental validation in CML and neuroblastoma

BREAST

LIVER

LUNG

OVARY

PANCREAS

STOMACH

NEUROBLASTOMA

NTRK1+

BAK1+

CD44-

BAK1+

LGALS3+

STAT3+

AKT1-

  

AKT1-

NTRK1+

LGALS3BP+

SRC+

ANGPTL4-

   

STAT1+

RELA+

 

ATM-

    

SRC+

 

DFFB-

    

STAT1+

 

HTATIP2-

    

STAT3+

 

NFKBIA-

    

BAD+

 

BCL2+

    

PDCD4-

 

BID+

    

CLU-

 

BIRC5+

      

CSE1L+

      

CYCS+

      

DAXX+

      

GRB2+

      

IL1R1+

      

RB1+

  1. The sign + indicates the potential gain according to CGH data and up regulation in transcripts and proteins, while – indicates the potential loss according to CGH and down regulation of transcripts and proteins.