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Table 3 Top hubs differentially activated in the DI network

From: Network analysis of human glaucomatous optic nerve head astrocytes

network hubs hub type edges in out
up-regulated hubs
SP1 TF 58 7 53
VDR TF 40 7 33
NF-kB TF 32 5 27
AP1 TF 21 2 19
AR TF 18 9 8
c-Fos TF 19 10 9
IGF-1 growth factor 17 7 10
c-Myb TF 14 7 7
STAT5B TF 13 9 4
HNF4-alpha TF 12 3 9
E2A TF 12 4 8
IL8 cytokine 11 10 1
MMP2 protease 10 8 2
down-regulated hubs
Interferon-gamma growth factor 19 3 16
STAT1 TF 17 6 11
c-Myb TF 6 0 6
PAI1 ligand 5 3 2