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Table 7 Comparison of the hub structure in the DI networks built from the three data sets and the combined set

From: Network analysis of human glaucomatous optic nerve head astrocytes

DI networks

DE set

DE up/down

G-set

G/DE combined

SP1*

.SP1*

TNFα

SP1*

VDR*

HNF-4α*

c-Jun*

c-Jun*

NF-kB*

AR*

ET-1

P53*

AP-1*

NF-kB*

STAT3*

VDR*

AR*

AP-1*

IL-1β

STAT1*

c-Fos*

STAT1*

AP-1*

AP-1*

STAT5*

c-Fos*

c-Fos*

TNFα

HNF-4α*

c-Rel*

EGFR

IL-1β

c-Myb*

VDR*

P53*

EGFR

IGF-1*

c-Myb*

iNOS

IFNγ

  1. *transcriptional factors
  2. bolded, top scored hubs shared by most networks