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Figure 4 | BMC Medical Genomics

Figure 4

From: MLL rearrangements in pediatric acute lymphoblastic and myeloblastic leukemias: MLL specific and lineage specific signatures

Figure 4

Genes involved in pro-B cell differentiation and proliferation. Regulatory role of PAX5 in B cell differentiation and proliferation. Up-regulated and down-regulated genes in ALL/MLL+ from supervised analyses are depicted red and green, respectively. The minimal self-sustaining gene regulatory module was obtained by Medina K. et al. [36] and expanded according to our results. The graph was generated using Ingenuity Pathways Analysis (IPA) software (Ingenuity® System, http://www.ingenuity.com).

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BMC Medical Genomics

ISSN: 1755-8794

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