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Archived Comments for: NMD inhibition fails to identify tumour suppressor genes in microsatellite stable gastric cancer cell lines

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  1. PTPRJ mutation

    Rodolfo Iuliano, Università di Catanzaro

    8 July 2009

    Buffart et al. in this paper affirm that they found a mutation (Glu836Asp) in PTPRJ gene. They reported the sequence of the region surrounding the mutation and, indeed, the sequence perfectly matches with that of exon 13 that includes a well known polymorphism of PTPRJ (Asp872Glu, SNP ID rs 4752904). Thus, also in this case, as correctly reported for the other two polymorphisms of PTPRJ, the authors detected a polymorphism and not a mutation of PTPRJ.

    Competing interests

    None declared