Table 3 List of 12 candidate genes putatively inactivated by nonsense mutation, including their chromosomal location, the cell line where it was identified and a short description of the gene.
Gene | Location | Cell line | Description |
|---|---|---|---|
PLA2G4A | 1q31.1 | GP202 | phospholipase A2, group IVA |
INHBB | 2q14,2 | IPA220 | Inhibin, beta B |
CSTA | 3q21.1 | GP202 | Cystatin A |
BMP5 | 6p12.1 | GP202 | Bone morphogenetic protein 5 |
MMP6 | 7p15.3 | GP202 | membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) |
FOXK1 | 7p22.1 | IPA220 | Forkhead box K1 |
PTPRJ | 11p11.2 | IPA220 | Protein tyrosine phosphatase, receptor type J |
KCNMB4 | 12q15 | GP202 | Potassium channel, calcium-activated, large conductance, subfamily M, beta member 4 |
SLITRK6 | 13q31.1 | GP202, IPA220 | SLIT and NTRK-like family, member 6 |
SNN | 16p13 | IPA220 | stannin |
TXNL4B | 16q22.2 | IPA220 | Thioredoxin-like 4B |
DYM | 18q21.1 | GP202 | dymecelin |