Table 1 Characteristics of the breast cancer cases, the healthy controls and their serum samples
|
Breast cancer cases (n = 48) |
Healthy controls (n = 48) | |
|---|---|---|
| Age (years) | ||
| Mean (± SD) | 58 (± 14) | 53 (± 9) |
| Menopause status, n (%) | ||
| Pre | 16 (33) | - |
| Post | 30 (63) | - |
| Missing | 2 (4) | 48 (100) |
| Sample storage duration (months) | ||
| Median (IQR) | 16 (11–35) | 17 (11–31) |
| Time from diagnosis to blood sampling (days) | ||
| Median (IQR) | 7 (0–20) | |
| Stage, n (%) | ||
| IIA | 26 (54) | |
| IIB | 11 (23) | |
| IIIA | 6 (13) | |
| IIIC | 5 (10) | |
| Tumor size, n (%) | ||
| > 0.5 – 1 cm | 2 (4) | |
| > 1 – 2 cm | 16 (33) | |
| > 2 – 5 cm | 28 (58) | |
| > 5 cm | 2 (4) | |
| Lymph node involvement, n (%) | ||
| No | 9 (19) | |
| 1–3 | 29 (60) | |
| > 3 | 10 (21) | |
| Differentiation, n (%) | ||
| High | 6 (13) | |
| Intermediate | 19 (40) | |
| Low | 22 (46) | |
| Unknown | 1 (2) | |
| ER status, n (%) | ||
| Negative | 13 (27) | |
| Positive | 35 (73) | |
| PR status, n (%) | ||
| Negative | 20 (42) | |
| Positive | 28 (58) | |
| Her2/neu expression, n (%) | ||
| Negative | 36 (75) | |
| Positive | 12 (25) | |
| P53 expression, n (%) | ||
| Negative | 18 (38) | |
| Positive | 24 (50) | |
| Missing | 6 (13) |