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Table 1 Characteristics of the breast cancer cases, the healthy controls and their serum samples

From: Validation of previously identified serum biomarkers for breast cancer with SELDI-TOF MS: a case control study

 

Breast cancer cases

(n = 48)

Healthy controls

(n = 48)

Age (years)

  

   Mean (± SD)

58 (± 14)

53 (± 9)

Menopause status, n (%)

  

   Pre

16 (33)

-

   Post

30 (63)

-

   Missing

2 (4)

48 (100)

Sample storage duration (months)

  

   Median (IQR)

16 (11–35)

17 (11–31)

Time from diagnosis to blood sampling (days)

  

   Median (IQR)

7 (0–20)

 

Stage, n (%)

  

   IIA

26 (54)

 

   IIB

11 (23)

 

   IIIA

6 (13)

 

   IIIC

5 (10)

 

Tumor size, n (%)

  

   > 0.5 – 1 cm

2 (4)

 

   > 1 – 2 cm

16 (33)

 

   > 2 – 5 cm

28 (58)

 

   > 5 cm

2 (4)

 

Lymph node involvement, n (%)

  

   No

9 (19)

 

   1–3

29 (60)

 

   > 3

10 (21)

 

Differentiation, n (%)

  

   High

6 (13)

 

   Intermediate

19 (40)

 

   Low

22 (46)

 

   Unknown

1 (2)

 

ER status, n (%)

  

   Negative

13 (27)

 

   Positive

35 (73)

 

PR status, n (%)

  

   Negative

20 (42)

 

   Positive

28 (58)

 

Her2/neu expression, n (%)

  

   Negative

36 (75)

 

   Positive

12 (25)

 

P53 expression, n (%)

  

   Negative

18 (38)

 

   Positive

24 (50)

 

   Missing

6 (13)

 
  1. SD = Standard Deviation, IQR = Inter-Quartile Range, ER = Oestrogen Receptor, PR = Progesterone Receptor