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Table 1 Characteristics of the breast cancer cases, the healthy controls and their serum samples

From: Validation of previously identified serum biomarkers for breast cancer with SELDI-TOF MS: a case control study

  Breast cancer cases
(n = 48)
Healthy controls
(n = 48)
Age (years)   
   Mean (± SD) 58 (± 14) 53 (± 9)
Menopause status, n (%)   
   Pre 16 (33) -
   Post 30 (63) -
   Missing 2 (4) 48 (100)
Sample storage duration (months)   
   Median (IQR) 16 (11–35) 17 (11–31)
Time from diagnosis to blood sampling (days)   
   Median (IQR) 7 (0–20)  
Stage, n (%)   
   IIA 26 (54)  
   IIB 11 (23)  
   IIIA 6 (13)  
   IIIC 5 (10)  
Tumor size, n (%)   
   > 0.5 – 1 cm 2 (4)  
   > 1 – 2 cm 16 (33)  
   > 2 – 5 cm 28 (58)  
   > 5 cm 2 (4)  
Lymph node involvement, n (%)   
   No 9 (19)  
   1–3 29 (60)  
   > 3 10 (21)  
Differentiation, n (%)   
   High 6 (13)  
   Intermediate 19 (40)  
   Low 22 (46)  
   Unknown 1 (2)  
ER status, n (%)   
   Negative 13 (27)  
   Positive 35 (73)  
PR status, n (%)   
   Negative 20 (42)  
   Positive 28 (58)  
Her2/neu expression, n (%)   
   Negative 36 (75)  
   Positive 12 (25)  
P53 expression, n (%)   
   Negative 18 (38)  
   Positive 24 (50)  
   Missing 6 (13)  
  1. SD = Standard Deviation, IQR = Inter-Quartile Range, ER = Oestrogen Receptor, PR = Progesterone Receptor