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Table 4 Oncogenes and tumor suppressor genes known to be associated with genomic changes in lung adenocarcinoma

From: Finding exclusively deleted or amplified genomic areas in lung adenocarcinomas using a novel chromosomal pattern analysis

Gene CNA class Cytoband Deletion (%) Amplification (%)
FHIT k = 3 (D) 3p14.2 52.3 1.5
LIMD1 k = 3 (D) 3p21.3 34.4 1.5
hTERT k = 7 (A) 5p15.33 6.2 55.4
SKP2 k = 7 (A) 5p13 1.5 38.5
EGFR-1 k = 7 (A) 7p11.2 1.5 24.6
c-MET k = 7 (A) 7q31 7.7 23.1
c-MYC k = 7 (A) 8q24.12-13 4.6 36.9
CDKN2A k = 3 (D) 9p21 29.2 6.2
PTEN k = 2 (D) 10q23.3 18.5 5.2
CCND1 k = 7 (A) 11q13 6.2 21.5
RB k = 3 (D) 13q14.2 43.1 1.5
NKX2-1 k = 7 (A) 14q13.3 3.1 21.5
WWOX k = 3 (D) 16q23.3-24.1 33.8 6.2
P53 k = 3 (D) 17p13.1 36.9 4.6
E2F k = 7 (A) 20q11.2 3.1 23.1