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Table 3 Biological Context

From: Host sequence motifs shared by HIV predict response to antiretroviral therapy

Category

Term

Count

%

p-value

GO BP Level 5

GO:0016310~phosphorylation

13

39.39%

5.21E-8

GO BP Level 5

GO:0008219~cell death

10

30.30%

7.86E-5

GO BP Level 5

GO:0006260~DNA replication

6

18.18%

9.30E-5

GO BP Level 5

GO:0006915~apoptosis

9

27.27%

3.16E-4

GO BP Level 5

GO:0006935~chemotaxis

5

15.15%

4.02E-4

GO MF Level 5

GO:0004697~protein kinase C activity

7

21.21%

1.22E-12

GO MF Level 5

GO:0004672~protein kinase activity

11

33.33%

1.75E-6

GO MF Level 5

GO:0032559~adenyl ribonucleotide binding

15

45.45%

1.97E-6

GO MF Level 5

GO:0003697~single-stranded DNA binding

5

15.15%

6.65E-6

GO MF Level 5

GO:0004707~MAP kinase activity

2

6.06%

0.0395

KEGG PATHWAY

hsa04650:Natural killer cell mediated cytotoxicity

10

30.30%

8.77E-9

KEGG PATHWAY

hsa04664:Fc epsilon RI signaling pathway

8

24.24%

1.30E-7

KEGG PATHWAY

hsa04530:Tight junction

9

27.27%

3.36E-7

KEGG PATHWAY

hsa04370:VEGF signaling pathway

7

21.21%

1.05E-6

KEGG PATHWAY

hsa04912:GnRH signaling pathway

6

18.18%

1.24E-4

KEGG PATHWAY

hsa05223:Non-small cell lung cancer

5

15.15%

1.34E-4

  1. Gene Ontology categories (level 5) and KEGG pathways associated with the host proteins listed in Table 2. Count refers to the number of proteins from Table 2 which have the associated term. P-values were determined using the DAVID enrichment tool using the set of all human proteins with the ELMs in Table 2 as a background set.