Table 2 Top 24 differentially regulated genes in response to DEX, FA, or TA treatment in TM 86 cell line.
Gene Symbol | Gene Name | GenBank Accession Number | DEX FC | FA FC | TA FC |
|---|---|---|---|---|---|
UPREGULATED | |||||
RGC32 | Response gene to complement 32 | NM_014059 | >100 | >100 | >100 |
OCA2 | oculocutaneous albinism II | NM_000275 | 70.2 | NS | NS |
SAA1 | Serum amyloid A1 | NM_000331 | 30.9 | 34.6 | 35.3 |
ANGPTL7 | Angiopoietin-like 7 | NM_021146 | 24.8 | 16.0 | 26.5 |
ITGA10 | Integrin, alpha 10 | NM_003637 | 22.4 | 25.1 | 17.7 |
LSP1 | clone pp9372 unknown mRNA | AF289610 | 20.9 | 14.9 | 15.4 |
KCNB1 | Potassium voltage-gated channel, Shab-related subfamily, member 1 | NM_004975 | 13.6 | 20.1 | 19.9 |
FKBP5 | FK506 binding protein 5 | NM_004117 | 12.9 | 13.8 | 12.5 |
KLF15 | Kruppel-like factor 15 | NM_014079 | 12.5 | 11.5 | 11.1 |
ANGPTL4 | Angiopoietin-like 4 | NM_139314 | 7.0 | 9.6 | 7.9 |
MYOC | Myocilin, trabecular meshwork inducible glucocorticoid response | NM_000261 | 7.5 | 7.4 | 6.7 |
ZBTB16 | Zinc finger and BTB domain containing 16 | NM_006006 | 7.5 | 8.7 | 8.1 |
PF4 | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | NM_002619 | NS | 3.2 | NS |
DOWNREGULATED | |||||
KAL1 | Kallmann syndrome 1 sequence | NM_000216 | -5.8 | -5.6 | -6.7 |
GABRB1 | Gamma-aminobutyric acid (GABA) A receptor, beta 1 | NM_000812 | -6.9 | -4.0 | -4.9 |
MXRA5 | Matrix-remodelling associated 5 | NM_015419 | -6.0 | -4.3 | -5.4 |
PER3 | Period homolog 3 (Drosophila) | NM_016831 | -5.1 | -5.3 | -7.0 |
AQP1 | Aquaporin 1 (Colton blood group) | NM_198098 | -5.5 | -4.4 | -5.1 |
PCDH19 | Protocadherin 19 | NM_020766 | -4.7 | -5.1 | -5.0 |
RASL11B | RAS-like, family 11, member B | NM_023940 | -4.0 | -4.9 | -4.0 |
KIF4A | Kinesin family member 4A | NM_012310 | -4.0 | -3.6 | -4.1 |
CXADR | Coxsackie virus and adenovirus receptor | NM_001338 | -4.7 | -3.4 | -4.8 |
CCRL1 | Chemokine (C-C motif) receptor-like 1 | NM_178445 | -3.8 | -4.7 | -3.4 |
ENST00000344214 | Unknown | Unknown | NS | NS | -3.1 |