Figure 3

Flowchart of cDNA microarray data analysis. Expression data were initially analyzed by planned linear contrast with a Benjamini-Hochberg correction yielding 35.3% of the probe sets on the microarray demonstrating significant differential gene expression (p < 0.01). Of these, 43.7% and 56.3% of the probe sets represented increased relative transcript abundance for repair tissue > normal cartilage and normal cartilage > repair tissue, respectively. When annotation is applied to these probe sets, 2688 (80.8%) have known gene symbols with a redundancy across this subset of probe sets equal to 21.8% yielding 2101 unique gene symbols.