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Table 8 The QPCR results showed a significant decrease in brain gene expression of GLS in subjects with schizophrenia compared to controls.

From: Exon expression in lymphoblastoid cell lines from subjects with schizophrenia before and after glucose deprivation

Genes BPD
FC
MDD
FC
SZ
FC
BPD versus C p-value MDD versus C p-value SZ versus C p-value
PDE4D 1.08 1.00 0.96 0.42 0.99 0.61
GLS 0.99 0.99 0.73 0.94 0.92 0.04
DSC2 0.99 1.06 0.97 0.93 0.40 0.66
DSC3 0.96 1.00 1.01 0.75 0.98 0.94
ADCY1 0.88 0.87 1.00 0.03 0.00 0.95
  1. No significant alterations of DLPFC gene expression in schizophrenia of any other transcript examined. BPD -- bipolar disorder; C -- control; MDD --major depressive disorder; SZ -- schizophrenia; FC -- Fold Change