Figure 6
Model of mastic oil action mechanisms in LLC cells. Schematic representation of target molecules and pathways underlying mastic oil-mediated chemopreventive effects on tumor cell proliferation, apoptosis and inflammation based on available literature (black arrows) and evidence as derived from the present study for LLC cells (red arrows). Dashed line indicates prediction of activity based on experimental evidence from mastic oil components. Numbers on arrows correspond to respective references indicated in the text and also interactions described in references [53–56].