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Table 2 Common TF motif families in cluster 2

From: A transcriptomic computational analysis of mastic oil-treated Lewis lung carcinomas reveals molecular mechanisms targeting tumor cell growth and survival

Family

p-value

% TF site containing promoters

V$CTCF

2.0652 × 10-8

80%

V$EGRF

2.0837 × 10-8

85%

V$ZBPF

3.3390 × 10-8

80%

V$AHRR

8.5552 × 10-8

69%

V$MAZF

2.0443 × 10-6

73%

V$SP1F

7.3263 × 10-6

85%

V$E2FF

1.6909 × 10-4

80%

V$EBOX

3.7640 × 10-3

69%

  1. Common statistically significant TF motif families found in proximal promoter sequences of genes contained in cluster 2, which are present in both mouse and human genomes. The column family refers to families of functionally similar motifs grouped together. The p-value is the probability to obtain a greater or equal number of sequences with a match in a random sample of the same size as the input sequence set. The percentage column depicts the percentage of genes in cluster 2 whose promoters have at least one match with the respective motif family. In each family identifier, V$ stands for "Vertebrates". Percentages and p-value calculations are based on mouse promoters.
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BMC Medical Genomics

ISSN: 1755-8794

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