Table 2 Differentially expressed genes after 5 min (Ca5), 20 min (Ca20) and 30 min (ca30) of untreated CA
Regulation | Known Function | Probe Set | Gene Products | Fold change | ||
|---|---|---|---|---|---|---|
| Â | Â | Â | Â | Ca5 | Ca20 | Ca30 |
Up | Transcription | Ssc.9200.1.A1_at | similar to ZCCHC12, Zinc finger CCHC domain-containing protein 12 | 1.3 | 2.1* | 1.3 |
| Â | Transcription | Ssc.2132.1.S1_a_at | similar to RPS6KA5 ribosomal protein S6 kinase alpha-5 | 0.8 | 2.3* | 1.0 |
| Â | Transcription | Ssc.22527.1.A1_at | similar to homeobox protein PBX3, Pre-B-cell leukemia transcription factor 3. | 0.9 | 2.5* | 1.3 |
| Â | Signal transduction | Ssc.14404.1.A1_at | HTR2C, 5-hydroxytryptamine (serotonin) receptor 2C | 1.1 | 4.6* | 1.5 |
| Â | Transport | Ssc.640.1.S1_at | TTR, Transthyretin (Prealbumin) | 27 | 2789* | 2.6 |
| Â | Cation transport | Ssc.3850.1.S1_at | similar to NNAT, neuronatin | 1.4 | 1.9* | 1.4 |
| Â | Potassium transport | Ssc.6932.1.A1_at | similar to DPP10, inactive dipeptidyl peptidase 10 | 1.3 | 1.1 | 1.5* |
| Â | Zinc transport | Ssc.7040.1.A1_at | similar to SLC30A9, solute carrier family 30 member 9 | 1.4 | 1.1 | 1.5* |
| Â | Zinc transport | Ssc.17849.1.A1_at | similar to SLC30A10, solute carrier family 30 member 10 | 4.0* | 4.5* | 4.7* |
| Â | Calcium-mediated signalling | Ssc.29371.1.A1_at | similar to GNAL guanine nucleotide-binding protein G(olf) subunit alpha | 1.6 | 16.5* | 1.1 |
| Â | Calcium-mediated signalling | Ssc.19549.1.S1_at | similar to NECAB1, Neuronal calcium-binding protein 1 | 1.5 | 1.0 | 2.0* |
| Â | Calcium-mediated signalling | Ssc.3649.1.A1_at | similar to RCAN3 regulator of calcineurin 3 (calcipressin-3) | 1.1 | 1.5* | 1.0 |
| Â | Opioid peptide | Ssc.121.1.S1_at | PDYN, Beta-neoendorphin-dynorphin | 6.2 | 14.2* | 1.4 |
| Â | Stress response | Ssc.7903.1.A1_at | similar to HSPA13, Heat shock 70 kDa protein 13 (stress 70 protein chaperone microsome-associated 60 kDa protein) | 1.3 | 0.9 | 2.0* |
| Â | Neurogenesis | Ssc.19425.1.A1_at | similar to MAPT, microtubule-associated protein tau | 1.7* | 1.0 | 1.2 |
| Â | Nucleic acid metabolism | Ssc.6238.2.S1_at | similar to AK3, GTP:AMP phosphotransferase mitochondrial (adenylate kinase 3) | 1.3 | 1.1 | 1.7* |
| Â | Not determined | Ssc.12504.1.A1_at | similar to protein FAM14A | 0.9 | 2.0* | 0.9 |
| Â | Not determined | Ssc.30063.1.A1_at | unknown | 2.4* | 1.0 | 1.0 |
| Â | Not determined | Ssc.29510.1.A1_at | unknown | 1.6 | 1.4 | 2.1* |
| Â | Not determined | Ssc.21096.1.S1_at | unknown | 1.3 | 3.6* | 4.5* |
| Â | Not determined | Ssc.31095.1.A1_at | unknown | 1.3 | 2.0* | 0.9 |
Down | Transcription | Ssc.19152.1.S1_at | similar to CPSF7, cleavage and polyadenylation specificity factor 7 | 0.8 | 0.8 | 0.6* |
| Â | Signal transduction | Ssc.13752.1.S1_at | similar to PIK3R1, phosphatidylinositol 3-kinase p85 regulatory subunit alpha | 0.7 | 0.3* | 0.8 |
| Â | Signal transduction | Ssc.11787.1.S1_at | similar to RASSF2, Ras association domain-containing protein 2 | 0.9 | 0.6* | 0.8 |
| Â | Proteolysis | Ssc.3063.1.S1_at | similar to PITRM1, pitrilysin metalloproteinase 1 | 0.6* | 0.6* | 0.9 |
| Â | Glucose metabolism | Ssc.19476.2.A1_s_at | PYGM, Glycogen phosphorylase | 0.7 | 0.8 | 0.6* |
| Â | Immune response | Ssc.13778.1.S1_at | IgG, Immunoglobulin G, heavy chain | 0.5 | 0.8 | 0.1* |
| Â | Not determined | Ssc.17442.1.S1_at | unknown | 0.9 | 0.6* | 0.6* |