Table 1 List of the first 35 decreased transcripts revealed by cDNA microarray analysis (ratio ATRX/control < 0.5).

1

putative lymphocyte G0/G1 switch or G0S2 gene

0.23

2

defensin, alpha 1, myeloid-related sequence

0.24

3

defensin, alpha 5, Paneth cell-specific

0.25

4

HAIK1 type I, intermediate filament cytocheratin or human Keratin 23 gene (KRT23)

0.26

5

tumor necrosis factor, alpha-induced protein 3

0.29

6

Oligophrenin-1 (the signal is probably reflecting cross-hybridization to GRAF1/OPHN-1-L, see text)

0.30

7

H.sapiens DNA for cyp related pseudogene

0.30

8

ESTs

0.31

9

DKFZP434N093 protein

0.33

10

XIAP associated factor-1

0.33

11

immediate early response 3

0.36

12

Homo sapiens clone 24407 mRNA sequence

0.36

13

v-jun avian sarcoma virus 17 oncogene homolog

0.37

14

small inducible cyt. Subfam. A (Cys-Cys), member 18, pulmonary and activation-regulated

0.39

15

regulator of G-protein signalling 1

0.40

16

branched chain aminotransferase 1, cytosolic

0.39

17

hypothetical protein FLJ23231

0.39

18

small inducible cytokine subfamily B (Cys-X-Cys), member 10

0.39

19

lactotransferrin

0.42

20

B-cell CLL/lymphoma 3

0.43

21

polymerase (RNA) III (DNA directed) (39 kD)

0.43

22

HS (clone B3B3E13) chrom 4p16.3 DNA fragment

0.43

23

RAB6 interacting, kinesin-like (rabkinesin6)

0.43

24

HS cDNA FLJ11918 fis, clone HEMBB1000272

0.44

25

DEAD/H (Asp-Glu-Ala-Asp/His) box polyp. 21

0.45

26

dual specificity phosphatase 2

0.44

27

hypothetical protein, expressed in osteoblast

0.44

28

hypothetical protein FLJ23306

0.48

29

interleukin 8

0.48

30

COX15 (yeast) homolog, cyt.c oxid. ass.protein

0.47

31

Incyte EST

0.49

32

hypoxia-ind. fact. 1, alpha sub (basic helix-loop-helix transcription factor)

0.48

33

dihydrolipoamide branched chain transacylase (E2 comp of branched chain keto acid dehyd. complex)

0.47

34

Human glucocorticoid receptor alpha mRNA, variant 3' UTR

0.47

35

ATP/GTP-binding protein

0.48