Annotation | Name | Accession | Fold Difference | |
---|---|---|---|---|
I Cytokine and chemokine-mediated immunity and signalling | Â | Â | lung i.n. vs spleen i.d. | lung i.n.vs lung i.d. |
CD40 antigen | Cd40 | NM_170702.2 | Â | 3.0 |
Chemokine (C motif) ligand 1 | Xcl1 | NM_008510.1 | 4.0 | 8.0 |
Chemokine (C-C motif) ligand 1 | Ccl1 | NM_011329.1 | 9.7 | 6.7 |
Chemokine (C-C motif) ligand 2 | Ccl2 | NM_011333.1 | 3.2 | 2.2 |
Chemokine (C-C motif) ligand 3 | Ccl3 | NM_011337.1 | Â | 4.3 |
Chemokine (C-C motif) ligand 4 | Ccl4 | NM_013652.1 | Â | 7.4 |
Chemokine (C-C motif) ligand 5 | Ccl5 | NM_013653.1 | Â | 3.4 |
Chemokine (C-C motif) ligand 7 | Ccl7 | NM_013654 | 17.9 | 6.9 |
Chemokine (C-C motif) ligand 8 | Ccl8 | NM_021443.1 | 10.7 | 4.3 |
Chemokine (C-C motif) ligand 12 | Ccl12 | NM_011331 | 2.7 | Â |
Chemokine (C-C motif) ligand 24 | Ccl24 | NM_019577.2 | -4.3 | Â |
Chemokine (C-X-C motif) ligand 1 | Cxcl1 | NM_008176.1 | 2.9 | Â |
Chemokine (C-X-C motif) ligand 2 | Cxcl2 | NM_009140 | 2.4 | Â |
Chemokine (C-X-C motif) ligand 9 | Cxcl9 | NM_008599 | Â | 12.6 |
Chemokine (C-C motif) receptor 3 | Ccr3 | NM_009914.2 | -2.1 | Â |
Chemokine (C-X-C motif) receptor 6 | Cxcr6 | NM_030712.1 | Â | 5.3 |
Colony stimulating factor 1 (macrophage) | Csf1 | NM_007778.1 | 2.1 | Â |
Colony stimulating factor 3 receptor (granulocyte) | Csf3r | NM_007782.1 | -2.1 | Â |
Cytokine inducible SH2-containing protein | Cish | NM_009895.2 | 4.7 | 4.5 |
Interferon gamma | Ifng | NM_008337.1 | Â | 5.2 |
Interferon gamma receptor 2 | Ifngr2 | NM_008338.2 | 3.2 | Â |
Interleukin 18 | Il18 | NM_008360.1 | -4.3 | Â |
Lymphocyte-activation gene 3 | Lag3 | NM_008479.1 | 2.8 | 5.0 |
Protein tyrosine phosphatase, non-receptor type 6 | Hcph | NM_013545.1 | Â | 2.0 |
Signal-regulatory protein alpha | Ptp4a3 | NM_008975.2 | -2.1 | Â |
Transferrin | Trf | NM_133977.1 | -8.8 | Â |
Tumor necrosis factor | Tnf | NM_013693 | Â | 2.6 |
II Inflammation mediated pathway | Â | Â | Â | Â |
Cyclin-dependent kinase inhibitor 1A (P21) | Cdkn1a | NM_007669.2 | 2.2 | Â |
Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog | Fgr | NM_010208 | -3.5 | Â |
Integrin alpha 9 | Itga9 | NM_133721.1 | -3.0 | Â |
Procollagen, type XIV, alpha 1 | Col14a1 | AK052963 | -3.4 | Â |
Prostaglandin-endoperoxide synthase 1 | Ptgs1 | NM_008969.1 | -7.0 | Â |
Vav2 oncogene | Vav2 | NM_009500.1 | -3.7 | Â |
III Interferon-stimulated genes | Â | Â | Â | Â |
2'-5' oligoadenylate synthetase-like 2 | Oasl2 | NM_011854.1 | 4.0 | 3.3 |
2'-5' oligoadenylate synthetase 1G | Oas1g | NM_011852.2 | Â | 3.2 |
Guanylate nucleotide binding protein 1 | Gbp1 | NM_010259.1 | 2.2 | 5.5 |
Guanylate nucleotide binding protein 2 | Gbp2 | NM_010260.1 | Â | 4.4 |
Guanylate nucleotide binding protein 4 | Gbp4 | NM_018734.2 | Â | 3.2 |
Interferon activated gene 202B | Ifi202b | NM_008327.1 | Â | 2.4 |
Interferon-induced protein with tetratricopeptide repeats 2 | Ifit2 | NM_008332.2 | Â | 2.0 |
Interferon-induced protein with tetratricopeptide repeats 3 | Ifit3 | NM_010501.1 | Â | 3.9 |
Interferon regulatory factor 8 | Icsbp1 | NM_008320.2 | Â | 3.2 |
Signal transducer and activator of transcription 1 | Stat1 | NM_009283 | Â | 3.0 |
SLAM family member 8 | Slamf8 | XM_129596.2 | Â | 5.0 |
IV T cell activation | Â | Â | Â | Â |
Beta-2 microglobulin | B2m | NM_009735.2 | Â | 2.3 |
Cathepsin S | Ctss | NM_021281.1 | Â | 3.0 |
CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) | li | BC003476 | Â | 5.6 |
CD86 antigen | Cd86 | NM_019388.2 | -2.3 | 2.5 |
CD274 antigen | Pdcd1lg1 | NM_021893.2 | 2.5 | 3.8 |
Cytotoxic T-lymphocyte-associated protein 4 | Ctla4 | NM_009843.2 | Â | 3.9 |
Histocompatibility 2, Q region locus 6 | H2-Q6 | NM_207648 | Â | 3.0 |
Interferon gamma inducible protein 30 | Ifi30 | NM_023065.2 | Â | 2.5 |
Histocompatibility 2, class II antigen A, beta 1 | H2-Ab1 | NM_207105.1 | Â | 7.7 |
Histocompatibility 2, D region locus 1 | H2-D1 | NM_010380.2 | Â | 3.0 |
Histocompatibility 2, class II, locus Dma | H2-DMa | NM_010386 | Â | 3.9 |
Histocompatibility 2, class II, locus Mb1 | H2-DMb1 | NM_010387.2 | Â | 5.8 |
Histocompatibility 2, class II, locus Mb2 | H2-DMb2 | NM_010388 | Â | 5.5 |
Histocompatibility 2, class II antigen E alpha | H2-Ea | NM_010381.2 | Â | 6.5 |
Histocompatibility 2, class II antigen E beta | H2-Eb1 | NM_010382.1 | Â | 7.9 |
Histocompatibility 2, K1, K region | H2-K1 | NM_001001892.1 | Â | 3.0 |
Histocompatibility 2, M region locus 3 | H2-M3 | NM_013819.1 | Â | 2.6 |
Histocompatibility 2, Q region locus 2 | H2-Q2 | NM_010392.2 | Â | 2.7 |
Histocompatibility 2, Q region locus 5 | H2-Q5 | NM_010393.1 | Â | 2.9 |
Histocompatibility 2, T region locus 10 | H2-T10 | NM_010395.5 | Â | 2.5 |
Histocompatibility 2, T region locus 23 | H2-T23 | NM_010398.1 | Â | 2.9 |
Histocompatibility 2, T region locus 9 | H2-T9 | NM_010399 | Â | 3.1 |
Peroxiredoxin 5 | Prdx5 | NM_012021 | Â | 2.2 |
V Other ligand-mediated signalling | Â | Â | Â | Â |
Calcitonin/calcitonin-related polypeptide, alpha | Calca | NM_007587 | 2.0 | Â |
E2F transcription factor 2 | E2f2 | NM_177733.2 | -3.4 | Â |
Endothelin 1 | Edn1 | NM_010104.2 | 2.1 | Â |
Endothelial differentiation, sphingolipid G-protein-coupled receptor, 5 | Edg5 | NM_010333 | Â | 2.1 |
FMS-like tyrosine kinase 1 | Flt1 | NM_010228.2 | 3.9 | Â |
Granulin | Grn | NM_008175.2 | Â | 2.8 |
Mannose-6-phosphate receptor, cation dependent | M6pr | NM_010749.4 | Â | 2.2 |
Paired-Ig-like receptor A1 | Pira1 | NM_011087.1 | -2.1 | Â |
Paired-Ig-like receptor A11 | Pira11 | NM_011088.1 | -2.1 | Â |
Paired-Ig-like receptor A3 | Pira3 | NM_011090.1 | -3.8 | Â |
Paired-Ig-like receptor A4 | Pira4 | NM_011091.1 | -2.4 | Â |
Peroxisome proliferator activated receptor gamma | Pparg | NM_011146.1 | -2.7 | Â |
Pre-B-cell colony-enhancing factor 1 | Pbef1 | NM_021524.1 | Â | 2.7 |
Secretoglobin, family 1A, member 1 (uteroglobin) | Scgbla1 | NM_011681.1 | 40.0 | Â |
Solute carrier family 1 (glial high affinity glutamate transporter), member 3 | Slcla3 | NM_148938.2 | -2.5 | Â |
Spermine oxidase | Smox | NM_145533.1 | -2.7 | Â |
Vascular endothelial growth factor A | Vegfa | NM_009505.2 | 2.5 | Â |
VI Complement-mediated | Â | Â | Â | Â |
Complement component 1, q subcomponent, alpha polypeptide | C1qa | NM_007572 | -3.6 | Â |
Complement component 1, q subcomponent, beta polypeptide | C1qb | NM_009777.1 | -4.5 | 3.8 |
Complement component 1, q subcomponent, C chain | C1qg | NM_007574.1 | -4.3 | Â |
Complement component 2 (within H-2S) | C2 | NM_013484.1 | -3.3 | Â |
Complement component 3 | C3 | NM_009778.1 | Â | 4.2 |
Complement component 4A (Rodgers blood group) | Slp | NM_011413 | 2.3 | Â |
Complement component 6 | C6 | NM_016704.1 | -2.6 | Â |
Complement factor B | H2-Bf | NM_008198.1 | 11.5 | 6.5 |
Complement factor properdin | Pfc | XM_135820.3 | -10.3 | Â |
Four and a half LIM domains 1 | Fhl1 | NM_010211.1 | 2.3 | Â |
VII Apoptosis | Â | Â | Â | Â |
B-cell leukemia/lymphoma 2 related protein A1b | Bcl2a1b | NM_007534 | Â | 2.5 |
B-cell leukemia/lymphoma 2 related protein A1d | Bcl2a1d | NM_007536 | Â | 2.7 |
Caspase 1 | Casp1 | NM_009807.1 | Â | 4.0 |
Caspase 4, apoptosis-related cysteine peptidase | Casp4 | NM_007609.1 | Â | 2.4 |
Epithelial membrane protein 3 | Emp3 | NM_010129.1 | Â | 2.3 |
Lectin, galactose binding, soluble 1 | Lgals1 | NM_008495.1 | Â | 4.0 |
Thioredoxin 1 | Txn1 | NM_011660.3 | Â | 2.1 |
VIII Signal transduction | Â | Â | Â | Â |
AXL receptor tyrosine kinase | Axl | NM_009465.2 | -6.4 | Â |
C-mer proto-oncogene tyrosine kinase | Mertk | NM_008587 | -3.7 | Â |
C-type lectin domain family 4, member a1 | BC049354 | XM_194289.2 | -3.0 | Â |
C-type lectin domain family 4, member b1 | Clec4b1 | NM_027218.1 | -3.9 | Â |
C-type lectin domain family 4, member a3 | Clec4a3 | NM_153197.3 | -2.1 | Â |
CD63 antigen | Cd63 | NM_007653.1 | 3.3 | Â |
CD81 antigen | Cd81 | NM_133655.1 | -4.6 | Â |
CD93 antigen | C1qr1 | NM_010740.1 | 3.7 | Â |
CD207 antigen | Cd207 | NM_144943.2 | -2.2 | Â |
Chemokine (C-X-C motif) ligand 15 | Cxcl15 | NM_011339.1 | 5.0 | Â |
Colony stimulating factor 1 receptor | Csf1r | NM_007779.1 | -9.5 | Â |
Integrin beta 5 | Itgb5 | NM_010580 | -3.4 | Â |
Neutrophilic granule protein | Ngp | NM_008694.1 | -8.9 | Â |
Plasminogen activator, urokinase | Plau | NM_008873.2 | 2.2 | Â |
S100 calcium binding protein A9 (calgranulin B) | S100a9 | NM_009114.1 | -4.2 | Â |
Thrombomodulin | Thbd | NM_009378.1 | 4.6 | Â |
IX Other cell communication | Â | Â | Â | Â |
Cadherin 1 | Cdh1 | NM_009864.1 | 4.8 | 3.2 |
Hematological and neurological expressed sequence 1 | Hn1 | NM_008258.1 | Â | 2.3 |
Intercellular adhesion molecule | Icam1 | NM_010493.2 | Â | 2.3 |
Lectin, galactoside-binding, soluble, 3 binding protein | Lgals3bp | NM_011150.1 | Â | 4.0 |
Proteolipid protein 2 | Plp2 | NM_019755.2 | Â | 2.5 |
Purine-nucleoside phosphorylase | Pnp | NM_013632.2 | Â | 3.2 |
X Natural killer cell-mediated immunity | Â | Â | Â | |
Fc fragment of IgG, low affinity IIIa, receptor | Fcrl3 | NM_144559.1 | Â | 3.8 |
Killer cell lectin-like receptor subfamily C, member 1 | Klrc1 | NM_010652 | Â | 3.8 |
Killer cell lectin-like receptor subfamily K, member 1 | Klrk1 | NM_033078.2 | Â | 2.0 |
Natural killer cell group 7 sequence | Nkg7 | NM_024253.3 | Â | 3.7 |
XI Other host immune responses | Â | Â | Â | Â |
Allograft inflammatory factor 1 | Aif1 | NM_019467.2 | -2.8 | 2.7 |
ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | Abcc3 | XM_358306.1 | -10.6 | Â |
Carboxylesterase 3 | Ces3 | NM_053200.1 | 2.9 | Â |
Catalase | Cat | NM_009804.1 | -2.3 | Â |
Cathelicidin antimicrobial peptide | Camp | NM_009921.1 | -18.3 | Â |
Cathepsin E | Ctse | NM_007799 | -2.3 | Â |
CD59a antigen | Cd59a | NM_007652.2 | -3.0 | Â |
CD93 antigen | C1qr1 | NM_010740.1 | 3.7 | Â |
CD163 antigen | Cd163 | NM_053094.1 | -10.1 | Â |
CD244 natural killer cell receptor 2B4 | Cd244 | NM_018729 | -3.3 | Â |
Coagulation factor X | F10 | NM_007972.2 | 2.6 | Â |
Fc receptor, IgG, alpha chain transporter | Fcgrt | NM_010189.1 | -4.8 | Â |
Glutathione peroxidase 1 | Gpx1 | NM_008160.1 | -2.7 | Â |
Glutathione peroxidase 3 | Gpx3 | NM_008161.1 | -2.0 | Â |
Glutathione S-transferase, mu 2 | Gstm2 | NM_008183.2 | 5.0 | Â |
Glutathione S-transferase omega 1 | Gsto1 | NM_010362.1 | -2.1 | Â |
Guanine nucleotide binding protein (G protein), gamma 2 subunit | Gng2 | NM_010315.2 | Â | 2.9 |
Guanine nucleotide binding protein (G protein), gamma 10 | Gng10 | NM_025277 | Â | 2.4 |
Hemochromatosis | Hfe | NM_010424.2 | -5.3 | Â |
Immunoresponsive gene 1 | Irg1 | XM_127883 | 2.8 | Â |
Interferon, alpha-inducible protein 27 | 2310061N23Rik | NM_029803 | Â | 3.9 |
Interferon induced transmembrane protein 2 | Ifitm2 | NM_030694.1 | -2.0 | Â |
Interferon induced transmembrane protein 6 | Ifitm6 | XM_133956.3 | -5.0 | Â |
Kruppel-like factor 6 | Copeb | NM_011803.1 | Â | 2.5 |
Lipocalin 2 | Lcn2 | NM_008491.1 | -5.1 | Â |
LPS-induced TN factor | Litaf | NM_019980 | Â | 2.6 |
Lymphocyte antigen 96 | Ly96 | NM_016923.1 | -2.2 | Â |
Lysozyme | Lyzs | NM_017372 | 2.5 | Â |
Mannose receptor, C type 1 | Mrc1 | NM_008625.1 | -7.6 | Â |
Membrane-associated ring finger (C3HC4) 8 | Mir | NM_027920.3 | -2.2 | Â |
Myeloperoxidase | Mpo | NM_010824.1 | -3.3 | Â |
Peptidoglycan recognition protein 1 | Pglyrp1 | NM_009402.1 | -2.5 | Â |
Peripheral myelin protein | Pmp22 | NM_008885.1 | 3.5 | Â |
Peroxidasin homolog (Drosophila) | 2310075M15Rik | XM_283052 | 2.0 | Â |
Peroxiredoxin 2 | Prdx2 | NM_011563.2 | -3.5 | Â |
Peroxiredoxin 5 | Prdx5 | NM_012021 | Â | 2.4 |
Phytoceramidase, alkaline | Phca | NM_025408.1 | -2.1 | Â |
Prosaposin | Psap | NM_011179 | -2.1 | 2.3 |
Regulator of G-protein signaling 1 | Rgs1 | NM_016846.2 | Â | 4.8 |
S100 calcium binding protein A4 | S100a4 | NM_011311.1 | Â | 4.6 |
S100 calcium binding protein A8 (calgranulin A) | S100a8 | NM_013650.1 | -4.4 | Â |
SAM domain and HD domain, 1 | Samhd1 | BC067198 | Â | 2.8 |
Selenoprotein P, plasma, 1 | Sepp1 | NM_009155.3 | -2.4 | Â |
Serum amyloid A 3 | Saa3 | NM_011315 | 4.5 | Â |
Solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | Slc11a1 | NM_013612.1 | -2.2 | Â |
Superoxide dismutase 2, mitochondrial | Sod2 | NM_013671.2 | Â | 2.9 |
Surfactant associated protein A1 | Sftpa1 | NM_023134.3 | 2.5 | Â |
Surfactant associated protein D | Sftpd | NM_009160.1 | 10.4 | Â |
XII Genes mentioned in text but not categorized by Panther | Â | Â | ||
Chemokine (C-X-C motif) ligand 12 | Cxcl12 | NM_013655.2 | 4.0 | Â |
Chemokine (C-X-C motif) ligand 13 | Cxcl13 | NM_018866.1 | 2.1 | Â |
Chemokine (C-X-C motif) ligand 16 | Cxcl16 | NM_023158 | Â | 4.1 |
Expressed sequence AA467197 | AA467197 | NM_001004174.1 | Â | 8.8 |
Lymphocyte antigen 6 complex, locus A | Ly6a | NM_010738.2 | 5.8 | 4.7 |
Immunity-related GTPase family, M | Irgm | NM_008326.1 | Â | 2.8 |
Lymphocyte antigen 6 complex, locus C | Ly6c | NM_010741 | Â | 3.0 |
Mus musculus lactotransferrin | Ltf | NM_08522.2 | -16.8 | Â |
Proteasome (prosome, macropain) subunit, beta type 9 | Psmb9 | NM_013585.1 | Â | 2.9 |
Proteasome (prosome, macropain) subunit, beta type 8 | Psmb8 | NM_010724 | Â | 3.2 |
Proteasome (prosome, macropain) subunit, beta type 10 | Psmb10 | NM_013640.1 | Â | 2.4 |
Serine (or cysteine) peptidase inhibitor, clade A, member 3G | Serpina3g | NM_009251.1 | Â | 14.8 |
Three prime repair exonuclease 1 | Trex1 | NM_011637.4 | Â | 2.0 |
Tryptophanyl-tRNA synthetase | Wars | NM_011710.2 | Â | 2.2 |
Tumor necrosis factor (ligand) superfamily, member 13b | Tnfsf13b | NM_033622 | 3.1 | 3.0 |
Ubiquitin D (Ubd) | Ubd | NM_023137.2 | Â | 4.2 |
Ubiquitin specific peptidase 18 | Usp18 | NM_011909.1 | Â | 2.6 |