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Table 3 Enriched functions of 1,026 ROS-diabetes targets

From: Literature-based discovery of diabetes- and ROS-related targets

Category Term #target p-value Fold
Biological Processes GO metabolic process 113 3.40E-26 3.3
  protein amino acid phosphorylation 98 2.90E-24 3.5
  response to hypoxia 36 8.80E-24 12
Molecular Functions GO protein binding 514 2.80E-71 2.1
  oxidoreductase activity 103 1.50E-31 4.2
  transferase activity 148 1.70E-26 2.7
Cellular Components GO cytoplasm 381 1.50E-57 2.3
  extracellular region 220 9.10E-44 2.9
  mitochondrion 154 6.30E-43 3.9
Pathway Focal adhesion 75 2.40E-42 9.4
  Apoptosis 49 6.70E-35 14.5
  MAPK signaling pathway 73 4.30E-34 6.9
  1. '#target' refers to the number of ROS-diabetes targets with each biological function with Benjamini-Hochberg adjusted p-values. Fold is the ratio of targets from the ROS-diabetes set to the complete HUGO gene set.