Table 5 Enriched functions of the 53 over-represented targets in diabetes
From: Literature-based discovery of diabetes- and ROS-related targets
Category | Term | # target | p-value | Fold |
|---|---|---|---|---|
Biological Processes GO | superoxide metabolic process | 7 | 3.70E-15 | 303 |
| Â | electron transport | 13 | 1.50E-12 | 16 |
| Â | superoxide release | 5 | 4.20E-11 | 298 |
Molecular Functions GO | electron carrier activity | 15 | 1.80E-17 | 27 |
| Â | oxidoreductase activity | 18 | 2.20E-16 | 14 |
| Â | iron ion binding | 15 | 4.20E-16 | 21 |
Cellular Components GO | mitochondrion | 13 | 9.90E-08 | 6 |
| Â | extracellular space | 10 | 6.60E-07 | 8 |
| Â | soluble fraction | 7 | 3.20E-06 | 11 |
Pathway | Leukocyte transendothelial migration | 9 | 6.40E-12 | 36 |
| Â | Small cell lung cancer | 7 | 1.00E-09 | 38 |
| Â | Formation of Platelet plug | 6 | 1.10E-08 | 41 |