Figure 1

Complex isoforms observed in transcription-induced chimeras. TIC splicing events are shown by dashed arrows, labeled with splice distance and samples or ESTs with supporting alignments. Standard splicing is shown by solid lines. (A) Multiple isoforms observed for PLEKHO2-ANKDD1A TIC in the human brain reference (HBR) and universal human reference (UHR) samples. (B) Direct TIC splicing and TICs with multiple forms of intervening exons (labeled IE) for VAMP8-VAMP5, all observed in a single prostate sample N1. Shaded box represents an intervening exon found previously [5], but not in this study. (C) TIC with an intergenic exon between ARMCX5 and GPRASP2, all observed in N1.