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Table 1 PhenoBase.

From: Animal model integration to AutDB, a genetic database for autism

Category ID PhenoBase Category Relationship to Autism Relevance to Autism
1 General observations   
2 Social behavior Core behavioral phenotype: Social interactions DSM IV diagnostic criteria
3 Communications Core behavioral phenotype: Communications DSM IV diagnostic criteria
4 Repetitive behavior Core behavioral phenotype: Restricted interests & Repetitive behavior DSM IV diagnostic criteria
5 Maternal behavior Broader phenotype of social memory, affect & attachment  
6 Motor phenotype Auxiliary phenotype of ASD Turner et al., 2001 [24]
7 Sensory Auxiliary phenotype of ASD Geyer and Swedlow, 1998 [25]
8 Learning & memory Auxiliary phenotype of ASD  
9 Emotion Hypothesis: Dysfunction of amygdala Tsai, 1999 [26]
10 Seizure 25% cases Ballaban-Gil and Tuchman, 2000 [27]
11 Circadian sleep/wake cycle Auxiliary phenotype: sleep disturbances Harvey and Kennedy, 2002 [28]
12 Homeostasis Unresolved  
13 Inflammatory response Auxiliary phenotype of ASD  
14 Synaptic function Hypothesis: Imbalance in E/I ratio  
15 Neuroanatomy/Ultra- structure/Cytoarchitecture Macrocephaly Piven et al., 1992 [29]
16 Molecular profile Unresolved  
  1. Table depicting the 16 categories of PhenoBase, along with their relationships and relevance to autism.