Discriminating lymphomas and reactive lymphadenopathy in lymph node biopsies by gene expression profiling

BMC Medical Genomics

Table 4 The top 20 annotated classifier genes of cHL.

Accession number	Gene name	Symbol	Fold change
NM_006152	Lymphoid-restricted membrane protein	LRMP	2.83
NM_005582	CD180 molecule	CD180	1.65
NM_002382	MYC associated factor X	MAX	0.65
NM_006564	Chemokine (C-X-C motif) receptor 6	CXCR6	0.57
NM_017458	Major vault protein	MVP	0.55
NM_015364	Lymphocyte antigen 96	LY96	0.52
D17028	Prosaposin	PSAP	0.51
NM_000167	Glycerol kinase	GK	0.51
NM_018664	Basic leucine zipper transcription factor, ATF-like 3	BATF3	0.48
NM_006137	CD7 molecule	CD7	0.45
NM_006018	G protein-coupled receptor 109B	GPR109B	0.43
NM_000579	Chemokine (C-C motif) receptor 5	CCR5	0.40
NM_003329	Thioredoxin	TXN	0.36
M36693	Superoxide dismutase 2, mitochondrial	SOD2	0.34
NM_007315	Signal transducer and activator of transcription 1, 91 kDa	STAT1	0.34
M26123	Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	SERPINA1	0.33
NM_002258	Killer cell lectin-like receptor subfamily B, member 1	KLRB1	0.32
NM_002990	Chemokine (C-C motif) ligand 22	CCL22	0.29
NM_001276	Chitinase 3-like 1 (cartilage glycoprotein-39)	CHI3L1	0.24
NM_002987	Chemokine (C-C motif) ligand 17	CCL17	0.18

Genes are ranked from high to low fold change (differential expression in cHL versus remainder of samples).

ISSN: 1755-8794