The three gene sets (circles) found when comparing different categories of HT users with non-users. The partly overlapping circles show which genes were significant for one, two or all three HT categories. All three categories include users of systemic E2. Gene symbols in red denote genes up-regulated in users and gene symbols in green denote genes up-regulated in non-users. Among the 9 HT genes, LOC344178, SET, MGC4618 and MORC2 have FDR <0.28, the remaining 5 genes have FDR <0.25.