Figure 1

GO terms significantly associated to chromosomal regions frequently lost in cancers. Since a large number of GO terms are tested, the popular FDR method [34] was used to adjust the p-values for multiple-testing effects obtained when conducting a one-tailed test [14]. GO terms with p-values under a conventional threshold of p < 0.05 were represented as red octagons and GO terms under a more liberal 0.05 < p < 0.15 were represented as blue octagons. White squares represent non-significant terms connecting the significant terms found. The picture has been obtained using the GoGraphViewer utility of the Babelomics package http://www.babelomics.org[44].