Table 2 Patient characteristics according to expression data set
| Â | Tumor and normal pairs | UNC set, known % normal (UNC24) | NKI 295 | Naderi et al. | Wang et al. | Natrajan et al. |
|---|---|---|---|---|---|---|
Patients (n) | 55 | 24 | 295 | 135 | 286 | 48 |
Microarrays (n) | 118 | 24 | 295 | 307 | 286 | 48 |
Median RFS, months | 14 | 31 | 78.2 | 119.5 | 86 | NA |
missing RFS, n (%) | 33 | 6 | 0 | 1 | 0 | 48 |
Estrogen receptor status, n (%) | Â | Â | Â | Â | Â | Â |
   positive | 35 (63.6) | 15 (62.5) | 226 (76.6) | 93 (68.9) | 209 (73.1) | 25 (52.1) |
   negative | 18 (32.7) | 7 (29.2) | 69 (23.4) | 40 (29.6) | 77 (26.9) | 23 (47.9) |
   missing | 2 (3.6) | 2 (8.3) | 0 (0) | 2 (1.5) | 0 (0) | 0 (0) |
AGE, years | Â | Â | Â | Â | Â | Â |
mean (standard deviation) | 53.2 (13.9) | 59.8 (17.0) | 44.0 (5.5) | 56.9 (8.9) | 54 (12) | 55 (12.6) |
GRADE, n (%) | Â | Â | Â | Â | Â | Â |
   1 | 5 (9.1) | 2 (8.3) | 75 (25.4) | 35 (26.0) | 7 (2.0) | 0 (0) |
   2 | 16 (29.1) | 7 (29.2) | 101 (34.2) | 50 (37.0) | 42 (15.0) | 0 (0) |
   3 | 19 (34.5) | 14 (58.3) | 119 (40.3) | 49 (36.3) | 148 (52.0) | 48 (100.0) |
   missing | 15 (27.3) | 1 (4.2) | 0 (0) | 1 (0.7) | 89 (31.0) | 0 (0) |
TUMOR SIZE, n (%) | Â | Â | Â | Â | Â | Â |
   < = 2 | 17 (30.9) | 17 (70.8) | 155 (52.5) | 93 (68.9) | 278 (0) | 18 (37.5) |
   > 2 | 38 (69.1) | 6 (25) | 140 (47.5) | 41 (30.4) | 8 (0) | 30 (62.5) |
   missing | 0 (0) | 1 (4.2) | 0 (0) | 1 (0.7) | 0 (0) | 0 (0) |
NODE, n (%) | Â | Â | Â | Â | Â | Â |
   positive | 1 (1.8) | 14 (58.3) | 144 (48.8) | 43 (31.9) | 0 (0) | 23 (48.0) |
   negative | 54 (98.2) | 9 (37.5) | 151 (51.2) | 86 (63.7) | 286 (100) | 24 (50.0) |
   missing | 0 (0) | 1 (4.2) | 0 (0) | 6 (4.4) | 0(0) | 1 (2.0) |
TUMOR SUBTYPES, n (%) | Â | Â | Â | Â | Â | Â |
   normal | 4 (7.3) | 1 (4.2) | 8 (2.7) | 13 (9.6) | 15 (5.2) | 1 (2.0) |
   LumA | 23 (41.8) | 6 (25.0) | 167 (56.6) | 59 (43.7) | 138 (48.3) | 17 (35.4) |
   LumB | 9 (16.4) | 9 (37.5) | 51 (17.3) | 25 (18.5) | 51 (17.8) | 8 (16.7) |
   Her2 | 7 (12.7) | 3 (12.5) | 23 (7.8) | 21 (15.6) | 29 (10.1) | 9 (18.8) |
   Basal | 12 (21.8) | 5 (20.8) | 46 (15.6) | 17 (12.6) | 53 (18.5) | 13 (27.1) |