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Table 2 Patient characteristics according to expression data set

From: Systematic Bias in Genomic Classification Due to Contaminating Non-neoplastic Tissue in Breast Tumor Samples

  Tumor and normal pairs UNC set, known % normal (UNC24) NKI 295 Naderi et al. Wang et al. Natrajan et al.
Patients (n) 55 24 295 135 286 48
Microarrays (n) 118 24 295 307 286 48
Median RFS, months 14 31 78.2 119.5 86 NA
missing RFS, n (%) 33 6 0 1 0 48
Estrogen receptor status, n (%)       
   positive 35 (63.6) 15 (62.5) 226 (76.6) 93 (68.9) 209 (73.1) 25 (52.1)
   negative 18 (32.7) 7 (29.2) 69 (23.4) 40 (29.6) 77 (26.9) 23 (47.9)
   missing 2 (3.6) 2 (8.3) 0 (0) 2 (1.5) 0 (0) 0 (0)
AGE, years       
mean (standard deviation) 53.2 (13.9) 59.8 (17.0) 44.0 (5.5) 56.9 (8.9) 54 (12) 55 (12.6)
GRADE, n (%)       
   1 5 (9.1) 2 (8.3) 75 (25.4) 35 (26.0) 7 (2.0) 0 (0)
   2 16 (29.1) 7 (29.2) 101 (34.2) 50 (37.0) 42 (15.0) 0 (0)
   3 19 (34.5) 14 (58.3) 119 (40.3) 49 (36.3) 148 (52.0) 48 (100.0)
   missing 15 (27.3) 1 (4.2) 0 (0) 1 (0.7) 89 (31.0) 0 (0)
TUMOR SIZE, n (%)       
   < = 2 17 (30.9) 17 (70.8) 155 (52.5) 93 (68.9) 278 (0) 18 (37.5)
   > 2 38 (69.1) 6 (25) 140 (47.5) 41 (30.4) 8 (0) 30 (62.5)
   missing 0 (0) 1 (4.2) 0 (0) 1 (0.7) 0 (0) 0 (0)
NODE, n (%)       
   positive 1 (1.8) 14 (58.3) 144 (48.8) 43 (31.9) 0 (0) 23 (48.0)
   negative 54 (98.2) 9 (37.5) 151 (51.2) 86 (63.7) 286 (100) 24 (50.0)
   missing 0 (0) 1 (4.2) 0 (0) 6 (4.4) 0(0) 1 (2.0)
TUMOR SUBTYPES, n (%)       
   normal 4 (7.3) 1 (4.2) 8 (2.7) 13 (9.6) 15 (5.2) 1 (2.0)
   LumA 23 (41.8) 6 (25.0) 167 (56.6) 59 (43.7) 138 (48.3) 17 (35.4)
   LumB 9 (16.4) 9 (37.5) 51 (17.3) 25 (18.5) 51 (17.8) 8 (16.7)
   Her2 7 (12.7) 3 (12.5) 23 (7.8) 21 (15.6) 29 (10.1) 9 (18.8)
   Basal 12 (21.8) 5 (20.8) 46 (15.6) 17 (12.6) 53 (18.5) 13 (27.1)