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Table 8 GO significant terms down-regulated in ob/ob vs. WT, without significant changes in POKO vs. WT mice

From: Early peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell mass

Name Term size Odds ratio log Adj. pvalue
GO molecular function    
L-glutamine transmembrane transporter activity (GO:0015186) 5 4.55 1.27E-002
GO cellular component    
desmosome (GO:0030057) 24 2.47 2.39E-004
apical junction complex (GO:0043296) 132 1.82 1.17E-009
apicolateral plasma membrane (GO:0016327) 134 1.8 1.17E-009
tight junction (GO:0005923) 102 1.7 3.21E-006
cell-cell junction (GO:0005911) 219 1.4 2.54E-007
cell junction (GO:0030054) 540 0.88 1.57E-005
GO biological process    
cholesterol biosynthetic process (GO:0006695) 30 2.47 4.76E-004
sterol biosynthetic process (GO:0016126) 37 2.17 2.13E-003
tongue development (GO:0043586) 12 3.16 3.09E-003
glutamine transport (GO:0006868) 5 4.55 9,11E-003
  1. GO significant terms down-regulated in islets from ob/ob vs. WT mice (adjusted p-value ≤ 0.05), without significant changes in islets from POKO vs. WT mice.