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Table 8 GO significant terms down-regulated in ob/ob vs. WT, without significant changes in POKO vs. WT mice

From: Early peroxisome proliferator-activated receptor gamma regulated genes involved in expansion of pancreatic beta cell mass

Name

Term size

Odds ratio log

Adj. pvalue

GO molecular function

   

L-glutamine transmembrane transporter activity (GO:0015186)

5

4.55

1.27E-002

GO cellular component

   

desmosome (GO:0030057)

24

2.47

2.39E-004

apical junction complex (GO:0043296)

132

1.82

1.17E-009

apicolateral plasma membrane (GO:0016327)

134

1.8

1.17E-009

tight junction (GO:0005923)

102

1.7

3.21E-006

cell-cell junction (GO:0005911)

219

1.4

2.54E-007

cell junction (GO:0030054)

540

0.88

1.57E-005

GO biological process

   

cholesterol biosynthetic process (GO:0006695)

30

2.47

4.76E-004

sterol biosynthetic process (GO:0016126)

37

2.17

2.13E-003

tongue development (GO:0043586)

12

3.16

3.09E-003

glutamine transport (GO:0006868)

5

4.55

9,11E-003

  1. GO significant terms down-regulated in islets from ob/ob vs. WT mice (adjusted p-value ≤ 0.05), without significant changes in islets from POKO vs. WT mice.