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Table 7 Five random permutation models with higher R2 than the L1 model and the adjusted R2 when tested on the Infinium data-set

From: DNA methylation differences at growth related genes correlate with birth weight: a molecular signature linked to developmental origins of adult disease?

Data Set R2 Adjusted R2 and stability when tested on Infinium Data Genes in model Gene names
22 newborns, methylation at 1,536 CpGs assayed using Illumina's GoldenGate array 0.86 0.59 (46/48) ADAM9 ADAM metallopeptidase domain 9
    DPYSL3 dihydropyrimidinase-like 3
    FABP5 fatty acid binding protein 5
    HOXB4 homeobox B4
    MHC2TA CIITA, class II, major histocompatibility complex, transactivator
    PRO1853 C2orf56, chromosome 2 open reading frame 56
  0.82 negative GRB10 growth factor receptor-bound protein 10
    HRASLS3 PLA2G16, phospholipase A2, group XVI
    MYH14 myosin, heavy chain 14, non-muscle
    NM15555  
    WNT16 wingless-type MMTV integration site family, member 16
  0.81 0.48 (44/48) BEST1 bestrophin 1
    IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
    OSBPL5 oxysterol binding protein-like 5
    PAX3 paired box 3
    PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3
    SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
  0.80 0 (45/48) CBX1 chromobox homolog 1
    EOMES eomesodermin
    PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form)
    PIK3CG phosphoinositide-3-kinase, catalytic, gamma polypeptide
    SLC16A1 solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
    TMPO thymopoietin
  0.79 negative C11ORF15 TMEM9B, TMEM9 domain family, member B
    CCT3 chaperonin containing TCP1, subunit 3 (gamma)
    MYH9 myosin, heavy chain 9, non-muscle
    PROX1 prospero homeobox 1
    REST RE1-silencing transcription factor
    RPS2 ribosomal protein S2