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Table 9 Top ten genes whose transcript levels are correlated with methylation of CpG sites in MSX1, CDK2 and GRB10

From: DNA methylation differences at growth related genes correlate with birth weight: a molecular signature linked to developmental origins of adult disease?

Tissue Methylation Gene CpG ID Expression Gene Transcript ID Correlation1 Gene Name
Blood MSX1 cg14167596 APOE ILMN_1740938 0.76 Apolipoprotein E
   cg14167596 CGA ILMN_1734176 0.70 Glycoprotein Hormones, Alpha Polypeptide
   cg03199651 KRT6C ILMN_1754576 0.69 Keratin 6 C
   cg14167596 PAPPA ILMN_1721770 0.67 Protein Kinase C And Casein Kinase Substrate in Neurons 1
   cg14167596 PSG4 ILMN_1693397 0.67 Pregnancy Specific Beta-1-Glycoprotein 4
   cg26615830 DCN ILMN_2347145 0.65 Decorin
   cg14167596 PSG6 ILMN_2309615 0.65 Pregnancy Specific Beta-1-Glycoprotein 6
   cg14167596 CSH1 ILMN_1693617 0.65 Chorionic somatomammotropin hormone 1 (placental lactogen)
   cg14167596 GH2 ILMN_1659354 0.65 Growth Hormone 2
   cg14167596 ADAM12 ILMN_1726266 0.65 ADAM Metallopeptidase Domain 12
Placenta CDK2 cg04108502 CXCL11 ILMN_2067890 0.74 Chemokine (C-X-C Motif) Ligand 11
   cg04108502 HLA-DPB1 ILMN_1749070 0.70 Major Histocompatibility Complex, Classii, DP Beta 1
   cg04108502 CXCL9 ILMN_1745356 0.68 Chemokine (C-X-C Motif) Ligand 9
   cg04108502 GBP4 ILMN_1771385 0.68 Guanylate Binding Protein 4
   cg04108502 GBP5 ILMN_2114568 0.67 Guanylate Binding Protein 5
   cg04108502 UBD ILMN_1678841 0.66 Ubiquitin D
   cg04108502 VCY ILMN_1683872 0.66 Variable charge, Y-linked
   cg04108502 HLA-DRB3 ILMN_1717261 0.66 Major Histocompatibility Complex, Class II, DR Beta 3
   cg04108502 CD3D ILMN_2261416 0.65 CD3d molecule, delta (CD3-TCR complex)
   cg04108502 CETP ILMN_1681882 0.65 Cholesteryl ester transfer protein, plasma
  GRB10 cg20651681 SHROOM2 ILMN_1681777 0.68 Shroom Family Member 2
   cg20651681 MESDC1 ILMN_1781565 0.67 Mesoderm Development Candidate 1
   cg20651681 CCDC146 ILMN_1790555 0.67 Coiled-Coil Domain Containing 146
   cg20651681 VANGL2 ILMN_1715647 0.67 Vang-Like2 (Vangogh, Drosophila)
   cg06790324 SCG2 ILMN_1703178 0.66 Secretogranin II
   cg20651681 STGC3 ILMN_1807244 0.66 hypothetical STGC3
   cg06790324 ABHD14B ILMN_2227533 0.66 Ab Hydrolase Domain Containing 14B
   cg20651681 TLL1 ILMN_1699814 0.66 Tolloid-Like 1
   cg20651681 SOD1 ILMN_1662438 -0.65 Superoxide Dismutase 1, Soluble
   cg06790324 INPP5E ILMN_1811301 0.65 Inositol polyphosphate-5-phosphatase, 72 kDa
  1. Genes in bold have suggested role in fetal or placental growth and development
  2. 1 Pearson correlation coefficient (P ≤ 0.01)