Skip to main content


Figure 4 | BMC Medical Genomics

Figure 4

From: Fibroblasts from phenotypically normal palmar fascia exhibit molecular profiles highly similar to fibroblasts from active disease in Dupuytren's Contracture

Figure 4

Concordance Analysis of Individual Sample Profiles of Gene Expression. Concordance was calculated (Partek) using the initial dataset of 959 significant transcripts (log base 2) with similarity between samples derived through Euclidean distance based on Euclidian distance. Relative similarity among samples based on labeled origin is depicted through a color gradient where dark blue represents highest similarity of expression values on the scale diminishing across a gradient to the most different values represented in dark red color. The light blue color at the blue-red interface is indicative of sample identity. Based on this analysis, palmar fascia- [16] versus Dupuytren-derived fibroblast samples [712] exhibited highest similarity (blue), while both were substantially different from carpal tunnel-derived fibroblast [1318] expression profiles

Back to article page