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Table 4 Median methylation levels of NKX2-5, HAND1, and TBX20 in the TOF patients and controls

From: LINE-1 methylation status and its association with tetralogy of fallot in infants

Gene TOF (median, IQR1) Control (median, IQR) P 2
HAND1 30.5%, 20.8%–40.9%, n = 30 18.7%, 12.2%–24.8%, n =15 0.0006
TBX20 16.2%, 11.0%–24.1%, n =31 29.5%, 25.0%–38.9%, n =13 <0.0001
NKX2-5 30.5%, 18.4%–43.4%, n =25 20.0%, 13.6%–23.2%, n =13 0.018
  1. 1 IQR: interquartile range; 2Mann-Whitney U test was used.