Table 4 Median methylation levels of NKX2-5, HAND1, and TBX20 in the TOF patients and controls
From: LINE-1 methylation status and its association with tetralogy of fallot in infants
Gene | TOF (median, IQR1) | Control (median, IQR) | P 2 |
|---|---|---|---|
HAND1 | 30.5%, 20.8%–40.9%, n = 30 | 18.7%, 12.2%–24.8%, n =15 | 0.0006 |
TBX20 | 16.2%, 11.0%–24.1%, n =31 | 29.5%, 25.0%–38.9%, n =13 | <0.0001 |
NKX2-5 | 30.5%, 18.4%–43.4%, n =25 | 20.0%, 13.6%–23.2%, n =13 | 0.018 |